Exam 1: Infection and Shock Flashcards
Airborne isolation
- Negative airflow rooms required to prevent spread of microbes
- HEPA filter
- For TB, measles, chickenpox
Droplet isolation
Protect from droplets that may travel 3 feet but are not suspended for long periods
For influenza, mumps, pertussis, meningitis
Contact isolation
- For known or suspected infections transmitted by direct contact or contact with items in environment
- For MRSA, pediculosis, scabies, RSV, C. difficile
CDC prevention guidelines
- Practice hand hygiene, proper handwashing
- Personal protective equipment (PPE)
MRSA and VRE treatment and prevention
- Vancomycin
- Linezolid
Health teaching best way to decrease incidence
- Perform frequent hand hygiene, including use of hand sanitizers
- Avoid close contact with people with infectious wounds
- Avoid large crowds
- Avoid contaminated surfaces
- Use good overall hygiene
Management of Ebola in hospital
- IV fluid & electrolyte replacement
- Oxygen & ventilation support
- Blood pressure support
- Care & Comfort
- Symptomatic care
- Emotional support
Bioterrorism isolation
- Anthrax: Standard Precautions
- Botulism: Standard Precautions
- Plague: Droplet & Contact
- Smallpox: Standard, Contact & Airborne
Hypovolemic Shock etiology
- Total body fluid decreased
- Hemorrhage, Dehydration
Hypovolemic Shock symptoms
- Increased HR
- Decreased blood pressure
- Narrowed pulse pressure
- Postural hypotension
- Flat neck and hand veins in dependent positions
- Slow capillary refill
- Pale, cool, moist skin
- Decreased cardiac output/cardiac index (know numbers)
- Low central venous pressure (CVP)
- Decreased PAWP
- Increased SVR
- Increased RR (Decreased Paco2/Decreased Pao2)
Distributive shock etiology
- Blood volume distributed to interstitial tissues where it cannot circulate, deliver oxygen
- Caused by loss of sympathetic tone, blood vessel dilation, pooling of blood in venous and capillary beds, capillary leak
- Neural-induced distributive shock
Neurogenic - Chemical-induced distributive shock
Anaphylaxis, Sepsis, Capillary leak syndrome
Distributive shock from anaphylaxis symptoms
- Decreased BP
- Increased HR, tachycardia
- Increased RR, tachypnea
- Cough, dysphagia
- Hoarseness
- Stridor
- Wheezing
- Rales/rhonchi
- Restlessness, anxiety, apprehension
- Pruritis, erythema, urticaria
- Angioedema
- Decreased CO/CI
- Decreased CVP
- Decreased PAWP
- Decreased SVR
Distributive shock from neurogenic symptoms
- Hypotension
- Bradycardia
- Warm, dry, skin
- Hypothermia
- Bounding pulse
- Decreased CO/CI
- Decreased CVP
- Decreased PAWP
- Decreased SVR
Distributive shock from septic symptoms
- Increased HR
- Decreased BP
- Wide pulse pressure
- Full, bounding pulse
- Pink, warm, flushed skin
- Increased RR
- Crackles
- Change in sensorium
- Increased temperature
- Increased CO/CI
- Decreased SVR
- Decreased CVP
- Decreased PAWP
- Increased SvO2
Sepsis pathophysiology
When SIRS is a result of infection
Sepsis symptoms
- Temp> 38 C° or < 36° C
- HR > 90 bpm
- RR > 20 per min
- Altered mental status
- fluid balance > 20ml/kg in 24hrs
- Glucose >140 mg/dl
- WBC > 12,000/mm3, < 4,000/mm3, or > 10% bands
- Elevated C-reactive protein
- Elevated plasma procalcitonin
- SBP < 90 mm Hg or a decrease >40 mm Hg
- MAP < 70 mm Hg
- Svo2 > 70%
- CI > 3.5 L/m
- Serum lactate > 1 mmol/L
- Pao2/Fio2 < 300
- UOP < 0.5 ml/kg/hr
- Creatinine increase > 0.5 mg/dl
- INR > 1.5 or aPTT > 60 sec
- Absent bowel sounds, Ileus
- Platelet count < 100
- Hyperbilirubinemia > 4mg/dl