exam 1: fluids (SN) Flashcards

1
Q

Who is most at risk for fluid imblanaces?

A

Infants and elderly

FVO for elderly: heart failure and renal failure
FVD for elderly: dehydration and lack of thirst

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2
Q

Why does H2O gradually decrease throughout age?

A

because muscle mass works to hold water but muscle mass decreases in age

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3
Q

Three factors that mostly influence fluids? How do they work?

A

Muscle: hold unto water; skin and blood contain the highest amounts of water in the body
-younger people have higher percentage of body fluid than older people (because of muscle mass)

Body Fat: fat repels water
-obese pt have less fluids (less TBW) than those who are leaner; becoming most at risk for fluid imbalance like dehydration

Gender: men have more lean muscle mass than adipose tissues&raquo_space; retain more body fluid than women

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4
Q

Discuss Intracellular Fluid (ICF) and the electrolytes associated

A

Fluid inside the cell

key electrolyte: potassium as most abundant electrolyte inside the cell
-pulled from outside to inside
(THINK!!!! K+ing Potassium needs to be inside !! not outside !!)

2/3 of fluid in body is almost inside cell; mainly in skeletal muscle cells

ICF is where electrolytes are flowing to

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5
Q

Discuss Extracellular Fluid (ECF) and the electrolytes associated.

A

Fluid inside bl vessels, skin tissues and spinal cord (CSF)

1/3 of Body Fluid

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6
Q

Explain the associated main organs associated with gaining and losing fluids and what happens.

A

Kidneys (washing machines!!) : 8oz of urine in 3 hr
doors to body letting fluid out of body in to potty
Renal failure problems: if BUN and CREATINE are HIGH ; if only BUN means DEHYDRATION

Skin: sensible loses/perspirations (visible water and electrolyte losses)
-increases during: fever, heat stroke, thyroid crisis
-sodium, chloride, potassium electrolytes seen in sweat
-burn pt MOST at risk for FVD due to losing water from blister formation

Lungs: cause insensible loses
-monitor pt with respiratory alkalosis: has hyperventilation ‘kussmaul repsirations’
what happens: acid leaving body through carbon dioxide, leaving body in alkaline state

GI Tract: diarrhea and fistulas cause large fluid loses

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7
Q

Define diffusion

A

solute movement from greater to lesser concentration leading to equalization, occurring through random movement of ions and molecules
-exchange of O2 and CO2

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8
Q

Define osmosis

A

(wet version of diffusion)

movement of fluid from low to high solute concentration with eventual equalization

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9
Q

Filtration

A

movement of water and solutes from a higher to a lower hydrostatic pressure

-passage of water and electrolytes ; all about fluid (hydrostatic) pressure from pumping action of heart

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10
Q

Osmolality

A

concentration of the solution; how heavy and concentrated is it ?

normal bl plasma: 270-300 mOsm/kg

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11
Q

Isotonic Fluids

A

does not cause any fluid shifts outside of vascular spaces , fluid stays inside the blood vessels ; enough pressure in each side of the membrane

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12
Q

Hypertonic Fluids

A

osmolality greater than normal (>300 mOsm/L)
-suck fluid out of cell making it super skinny
-solution has osmotic pressure greater than in the body&raquo_space; that excess solution is being pulled out of the cell&raquo_space; into vascular blood vessels spaces
-done to dilute and equalize osmotic pressure from thick hypertonic fluid

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13
Q

Hypotonic Fluids

A

osmolarity less than normal ( <300 mOsm/L)
-osmotic pressure greater inside body&raquo_space; when infused, fluids out of the blood&raquo_space; into the cell

HYPO- HIPPO- BIG

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14
Q

Manifestations of:
Fluid Volume Overload (FVO)
Fluid Volume Excess (FVE)
Hypervolemia

A

leads to s/s of edema (see edema card)

high fluid volume = big bulging body
weight gain=water gain&raquo_space; may lead to pulmonary edema and massive fluids in lungs
2-3 lbs in 1d, 5lbs in 7d

cardio: high BP and HTN crisis
140 sys (hypertension) , 180 sys (stroke risk)
aneurysm, increased CVP, bounding pulses, JVD

integ: periorbital edema and pitting edema, pale cool skin

neuromuscular: ALOC due to “mental status changes”, headache (brain swelling&raquo_space; seizures), weakness, paresthesias (pins & needles)

renal and urinary: usually an increase urine output ; however, if there are renal issues, decreased urine output

lab values: LOW when liquidy
-low diluted lab values (hemodilution)
-decreased osmolality (decrease in thickness in blood)
-decreased electrolytes
SODIUM as most critical as severely low amount HYPONATREMIA can lead to severe brain problems/damage

REMEMBER!!
monitor sodium during FVO

GI: increased motility leading to diarrhea (bowel too fast) ; hepatomegaly (enlarged liver) and ascites (abdominal fluid: fluid has no where to go ! go to organs)

respiratory: rapid shallow rate with rales (moist cackles): indicating fluid in lungs
pulmonary edema

urine:
-decreased urine specific gravity
low gravity=low weight

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15
Q

Define edema and its manifestations.
Edema Pitting Points

A

def: swelling of soft tissues due to excess fluid accumulation
-common and noticeable in lower extremities: fluid pulls when pt is in upright position

0+ : no pitting edema
1+ : 2mm or less (mild edema) - immediate rebound
2+ : 3-4mm (moderate edema)- 15 secs rebound
3+ : 5-6mm (moderately severe edema)- 30 secs rebound
4+ : 8mm or deeper (severe edema)- 1-2 mins rebound

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16
Q

Top 4 causes of edema

A
  1. Increased hydrostatic pressure
    -high fluid pressure within blood vessels&raquo_space; causes fluid to be pushed out of blood vessel and in to interstitial space
    -high bp and pitting edema (worsening)
    ex. renal failure, heart failure
  2. Decreased osmotic pressure
    -decrease colloid in blood&raquo_space; decrease fluid retention inside blood vessels
    -colloid holds water in vascular space (low albumin=low plasma proteins= low Attraction of fluid
    fluid leaks out into body cavity)
  3. Increased capillary permeability
    edema from fluid leaking out to the blood vessel
    caused: severe inflammation or tissue destruction (bacteria-causing infection and burns)
  4. Obstruction of the lymphatic system
    -since lymphatic works to clean blood and get rid of any wastes with help of WBC&raquo_space; backup of fluid occurs
    cause: cancer or tube blockage or infection (big lymph nodes)
17
Q

Elaborate on major burns

A

-can cause massive tissue damage and cellular destruction&raquo_space; widespread systemic inflammation&raquo_space; increases vascular / capillary permeability
“leaky blood vessels that fill up body”

-fluids, electrolytes, and other components spill all over interstitial spaces = low fluid volume intravascularly as they escape and go into tissues&raquo_space; hypovolemic shock

FIRST intervention in first 24 hrs: IV LR solution and IV NS
-are isotonic fluids (since they stay inside veins longer closely resembling human blood )
-increases fluid volume inside fluid vessels&raquo_space; increasing blood pressure

18
Q

Fluid Volume Deficit (FVD) , causes, and 3 DDDs
Dehydration

A

-Pt has decrease in fluid

Causes:
-Vomiting & Diarrhea
-Hot body & Sweating: fever, heat stroke, thyroid crisis
-Severe burns: most at risk since a lot of fluids are lost due to blister formation in skin
-urination

DDDs:
DI (diabetic Insipidus): too much urine lost
DKA (diabetic ketoacidosis): increased sugar concentration in blood (hyperglycemia) ; caused by infection ; manifestation: kussumal respiration
Diuretics (furosemide, hydrochlorothiazide): -ide = dr- ied ; drain fluid from body into potty, there is loss of electrolytes (where fluid goes, electrolytes go!!)

19
Q

Compensation of FVD and Dehydration

A

-increased thirst
-concentrated urine (body holds unto urine)
-increased HR and Vasoconstriction

THINK !!
make up for decreased fluid volume&raquo_space; the very little amount of blood that there is is being pumped at a faster pace to reach all of the body&raquo_space; to perfuse or oxygenate tissues
^^ called COMPENSATORY MECHANISM

20
Q

Manifestations of Fluid Volume Deficit

A

low fluid volume = low body
weight loss = water loss

cardio: low BP can be deadly due to hypovolemic shock (can cause many organs to stop working)
orthostatic hypotension
decreased CVP, weak & thready pulses, flat neck & hand veins, tachycardia

integ: dry skin (poor turgor & tenting); sunken eyes, dry MM, increase body temp

neuromuscular: lethargy to come and weakness

renal & urinary: increase output initially & decreased urine output at end

respiratory: rapid deep rate

GI: decreased motility leading to constipation, diminished bowel sounds (hypoactive bowel sounds)

lab values: appear high when dry
-hemoconcentration of solutes inside blood&raquo_space; almost like paste
-increase osmolality (increased thickness)
-increased hematocrit
-increase electrolytes
Sodium most critical as severely high amount HYPERNATREMIA can lead to risk for brain bleeding (brain shrinkage)

urine:
increased urine specific gravity
high gravity=high weight
-very thick and concentration of urine

21
Q

Isotonic Solution of IVs

A

-no fluid shifts; established equilibrium or are equal in concentration = equal osmotic pressure
-human blood is isotonic ; little osmosis occurs when isotonic solutions are infused since they have the same osmolality as body fluids

caution: too much can still cause FVO, so monitor BP
key manifestation: HTN crisis&raquo_space; risk for CVA stroke

LR and IV NS
uses: add fluid inside blood vessel to hydrate body and increase BP when low
-during hypotension, blood transfusions (add volume during bl administration), hemorrhaging, DKA (type 1 disorder) and HHNS (type 2 disorder)
-hyperglycemia&raquo_space; blood very thick&raquo_space; body very dry

Start on isotonic solutions then move to hypotonic fluids

22
Q

Hypotonic Solutions of IV

A

-lower concentration of solutes than ICF
-lower osmolarity than body fluids

caution:
solutions should be given slowly to prevent cellular edema and cerebral swelling
not for: ICP (pressure within brain)

manifestation to monitor: cerebral edema
-headache, mental status changes (ALOC), and seizures

1/2 NS
1/4 NS
1/3 NS
D5W 1/4NS (5% dextrose in 0.225 NS)
D5W (5% dextrose in water)

uses: cellular dehydration
-esp hypernatremia (too much sodium that piles up inside bl stream sucking out all of fluid&raquo_space; causing cells to shrink (dehydration))

REMEMBER !! D5W is isotonic IN BAG but hypotonic OUTSIDE

23
Q

Hypertonic solutions of IV

A

higher osmolarity than body fluids
-very thick and salty solutions (more solutes and less water)

fluid draw out of cell to make balance causing cell to become dehydrated

caution: give slowly to prevent massive fluid shifts from inside of cell and into blood stream
causing cellular dehydration and FVO
Monitor BP
key manifestation: HTN crisis (risk for CVA stroke)

3% NS
5% NS
D10W
D5W/NS
D5W/ 1/2NS
D5LR

use: hypovolemia, heat related (heat exhaustion), peritonitis, peritoneal dialysis (COMMON)

24
Q

Homeostasis

A

body being in harmony and all systems are within a normal range

25
Q

Therapeutic range

A

range at which a therapeutic regimen is working its best

26
Q

Hemoconcentration v Hemodilation

A

Dehydration
High lab values and Dry body

Overhydration
Low lab values and Liquidy body