exam 1 Flashcards

0
Q

why do we have medullary cavities

A

lower wt, skeleton lighter. ex: sinuses reduce wt of head

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1
Q

yellow bone marrow

A

stores fat; supports blood vessels and nerves that travel through the living bone.

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2
Q

role of vitamin A

A

protein synthesis and a lot of making/maintaining matrix of bone is about making protein

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3
Q

osteoblastic hormones

A

thyrocalcitonin, somatotropin, testosterone, estrogen

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4
Q

osteoclastic hormones

A

parathormone, thyroxine, corticosteroids.

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5
Q

thyroid follicles

A

simple cuboidal epithelium; hormones say make more protein, rise in basal metabolic rate

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6
Q

thyrocalcitonin

A

calcium into bony matrix; lowers blood calcium b/c its going into the bone; lowers blood sugar

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7
Q

3 target tissues for calcitonin

A

bone/skeleton;intestine (block absorption from intestine if have too much)

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8
Q

hormone functions from thyroid gland

A

reg metabolic rate by telling cells how fast to produce proteins; body building activities

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9
Q

how to raise blood calcium

A

increase kidney absorption; release calcium from matrix by releasing osteoclasts to digest those matrix to thin the matrix; intestines absorb more

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10
Q

trebeculae

A

in spongy bone, 2 cells thick; get thin = osteoporosis; in femur, surgical neck (break on step, not on fall)

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11
Q

why are sex hormones considered osteoblastic?

A

corresponds with growth spurts (estrogen more powerful osteoblast than testosterone, hence girls grow first.)

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12
Q

fidoestrogens

A

plant chemicals close to estrogen

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13
Q

need vitamin d for?

A

transport calcium

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14
Q

corticosteriods

A

cortizone-like, bone density at risk

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15
Q

process to decrease blood calcium

A

activates vitamin d in kidneys; 1. increases absorption in intestine, 2. increases osteoclastic activity in skeleton, 3. increases reabsorption in kidneys.

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16
Q

types of fractures

A

spiral, compound, comminuated, greenstick, malunion, nonunion, delayed union, oblique, transverse

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17
Q

hematoma

A

blood clot

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18
Q

where does spongy bone form

A

close to developing blood vessels

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19
Q

fibrocartilage

A

more distant regions

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20
Q

osteoclasts

A

remove excess bone tissue, restore much like the original

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21
Q

types of membrane

A

serous, mucus, cutaneous, sinovial; organs

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22
Q

epidermis

A

simple squamous; stomach (top layer); multilayers; NOT a membrane

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23
Q

intramembranous

A

connective tissue pattern/template; membrane-like in that it;s flat (flat bones and flat portions of bones)

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24
Q

neuroglia

A

ectoderm; no axons and dendrites; supports and protects cells/tissues of nervous symptoms

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25
Q

endochondral bone formation

A

endro = sends chondroblasts to secrete a cartilage before the osteoblasts form the bony matrix (long bone formation)

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26
Q

mineralization

A

happens after the cartilage is laid, chondrocytes (cells of the cartilage) begin to die due to lack of nutrients and cant properly dispose of waste; where they die they leave holes (lacunae) for blood vessels to fill holes, send in osteoblasts, lay down bony matrix, spongy bone created, compact laid outside after spongy done.

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27
Q

perichondrium

A

protective layer of collagen on the outside of cartilage

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28
Q

periosteum

A

protective layer of cartilage on the outside of bone; has a really good blood flow

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29
Q

endosteum

A

protective layer around the inside of bone, both spongy and compact

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30
Q

primary ossification center

A

spongy bone in the middle of diaphysis, everything else is cartilage

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31
Q

secondary ossification centers

A

growing in both directions from both epiphyses

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32
Q

from which embryonic germ layer are the tissues of the bone derived?

A

mesoderm

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33
Q

-ase

A

enzyme

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34
Q

red marrow

A

create all the formed elements of blood

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35
Q

how bones grow in length

A

push cartilage towards diaphysis

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36
Q

how bones grow in width

A

periosteum

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37
Q

factors necessary for normal ossification

A

calcium, vitamin d, vitamin c, vitamin a, collagen fibers, pyrophosphotase, osteoclastic/osteoblastic hormones

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38
Q

general functions of the skin

A

regulate body temp, protection as a physical barrier

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39
Q

why is skin an organ

A

b/c has 2 types of tissues

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40
Q

sensory receptors

A

mechnoreceptory, thermoreceptors, pain receptors

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41
Q

outer layer of skin (epidermis)

A

stratified squamous epithelium

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42
Q

are there tight junctions in our skin?

A

no.

43
Q

materials that can cross epithelium of the skin

A

oils, things that are lipid soluable

44
Q

glands assoc. w/ skin

A

sweat glands, exocrine (secrete through ducts), sebaceous, ceruminous (water proofing, antimicrobial)

45
Q

origin of upper layers of epidermal cells

A

ectoderm

46
Q

dermis

A

comprised of connective tissues

47
Q

layers of the epidermis, from superficial to deep

A

stratum corneum (dead), stratum lucidum (hairless ares, hands and feet), stratum granulosum (dying), stratum spinosum, stratum basale (capable of mitosis), dermis

48
Q

osteogenesis

A

create bone

49
Q

mesenchymal cells

A

move to area of future bone and start to specialize; some become fibroblasts and others become osteoblasts

50
Q

intra membranous bone formation main aspects

A

fibroblasts and osteoblasts

51
Q

osteogenesis imperfecti

A

cannot make collagen normally

52
Q

why is smooth muscle called smooth?

A

no striations (still has actin and myosin, single centrally located nucleus, long spindle shape)

53
Q

goblet cells

A

secrete mucus; surrounded by columni

54
Q

avascular

A

w/o blood vessles

55
Q

transitional epithelial

A

changes number of layers

56
Q

pseudostratefied epithelium

A

looks stratefied (multiple cell layers) but, every cell touches bottom of that epithelim

57
Q

endocrine

A

hormones into blood stream

58
Q

exocrine

A

outside through ducts or into hollow lumen. sweat, bile, tears.

59
Q

goblet cells

A

unicellular exocrine gland that secretes into a cavity

60
Q

heterocrine

A

both endo/exo functions. ex: pancreas = part of digestive tract and releases insulin directly into blood stream

61
Q

lumen

A

space in any hollow organ/space

62
Q

basement membrane

A

noncellular glue like substance that adheres epithelium to underlying tissue (blisters)

63
Q

chemoreceptors

A

respond to changes in chemicals

64
Q

mechanoreceptors

A

respond to physical changes like stretch and pressure

65
Q

connective tissue

A

support, connect, insulate

66
Q

3 major cell types found in connective tissue

A

macrophage = big eaters, 1st line of defense
fibroblasts = make fibers
mast cells = promote inflammation; swelling (edema; fluid build up), redness (increased blood supply), heat, pus (mostly white blood cells to fight off infection/invasion), help stimulate w/ chem message, release histomine

67
Q

dermographia

A

skin writing

68
Q

types of connective tissue fibers

A

collagen, elastin, glycoprotein, reticular

69
Q

embryonic connective tissue origin

A

mesenchyme

70
Q

muscle tissue

A

cells that shorten due to the chemical and physical interaction b/w myofilaments (actin and myosin)

71
Q

types of muscle

A

skeletal, cardiac, smooth

72
Q

3 components of homeostatic mechnisms

A

receptor, control center, effectors

73
Q

effectors

A

glands muscle tissue (adrenal, pituitary, etc)

74
Q

negative feedback

A

produces opposite change so it pouts body back into homeostasis

75
Q

positive feedback

A

speeds up a change / return to homeostasis

76
Q

feedforward feedback

A

anticipates change (stomach: salivate before u start eating, bile produced when see/smell food.)

77
Q

what do receptors measure

A

rate of change and direction of change, not how much or how little.

78
Q

thrombus

A

blood clot; positive feedback mechanism; speeds up process of healing/clotting

79
Q

ectoderm specializations

A

nervous system, portions of eye and ear, tooth enamel, skin, hair

80
Q

mesoderm specialization

A

muscle tissue, heart, blood, bone, kidneys

81
Q

endoderm specialization

A

lining of gut, liver, pancreas, respiratory

82
Q

4 basic tissue types

A

nervous, epithelial, connective, muscular

83
Q

inter cellular junctions

A

tight (chicken pox; paper and glue), adherns (sticky), gap (barrel b/w 2 cells), desmosomes (shoelaces), hemidesmosome (shoe laces; only found near basement membrane)

84
Q

purpose of tissue fluid

A

let things through, move things around

85
Q

blood vessels that carry blood from heart

A

artery

86
Q

smallest blood vessel

A

capillaries

87
Q

boundary organs that get rid of waste

A

urinary respiratory digestive

88
Q

why might tissue fluid composition change?

A

concentration of solutes change; adding in or losing things at boundary organs

89
Q

cell membrane

A

selectively permeable

90
Q

how do things move accross capillary wall?

A

porous; blood flows through, pressure, pores don’t let big stuff through, but lets through smaller particles like glucose

91
Q

diffussion

A

through cell membrane

92
Q

bulk flow

A

material exchange w/o atp.

93
Q

electrolytes

A

sodium calcium potassium chloride

94
Q

aquaporins

A

water pores

95
Q

cell membrane function and composition

A

selectively permeable; water can move through at all times

96
Q

do cells sometimes transport proteins across cell membranes

A

yes, through active transport

97
Q

rough endoplasmic reticulum

A

produce protein

98
Q

storage organelles for most cells

A

modified smooth endoplasmic reticulum

99
Q

levels of organization

A

chemical, cellular, tissue, organ, organ system, organism

100
Q

kidneys

A

boundary organ; filter waste products and recycle water; urinary system

101
Q

3 boundary organ systems

A

digestive, respiratory, integumentary (skin)

102
Q

boundary organs contain…

A

selective transport epithelia

103
Q

NOT boundary organs

A

muscular, skeletal, endocrine, CNS, immune

104
Q

intermediary b/w boundary and other organs

A

tissue fluid

105
Q

intracellular fluid

A

within cells; tissue fluid (aka interstitial)

106
Q

extracellular fluid

A

plasma fluid portion of blood