Exam 1 Flashcards
 nerve cells that form the brain spinal cord and nerves that transmit electrical signals throughout the body
Neurons
Cell body of a neuron containing all the organelles needed to maintain the cell
Soma
Projections from the soma that receive signals and information from other cels
Dendrites
Long tubular extension from the soma of the nerve cell that conducts electrical signals away from the cel body and toward the axon terminals
Axon
The segment of axon adjacent to the soma where the action potential is first generated
Axon hillock
Small enlargements at the axon terminal, in close proximity to the postsynaptic cell, containing synaptic vesicles. Also known as boutons
Terminal buttons
Chemical substances packaged in synaptic vesicles and released by neurons to communicate across synapses with other neurons , muscles cells, secretory cells, or cells comprising other tissues/organs
Neurotransmitters
A fatty insulating sheath surrounding many axons that increases the speed of nerve conduction. It is produced by oligondendrocytes in the CNS and by Schwann cells in the peripheral nervous system
Myelin
Ion channels that are normally in a closed configuration that can be opened momentarily by specific stimuli
Gated channels
Type of ion channels that are regulated by volatage differences across the membrane
Voltage-gated channels
Group of ion channels that are regulated by a ligand binding to a receptor site associated with that channel
Ligand-gated channels
Glial cells that myelinate perirpheral nerve axons
Schwann cells
Star shaped glial cells that have numerous extensions and that modulate the chemical environment around neurons, metabolically assist neurons, and provide phagocytosis for cellular debris
Astrocytes
Small nonneuronal cels in the CNS that collect at points of cell damage or inflammation and demonstrate phagocytosis behavior
Microglia
The difference in the electrical charge inside a neuron at rest compared to the outside. The inside of the cell is more negative, and that potential is -70mV
Resting membrane potential
Force drawing an ion to either side of the cell membrane in an attempt to balance or neutralize ionic charges
Electrostatic pressure
Major depolarization generated in the axon hillock that is transmitted down the axon
Action potential
Membrane potential, typically -50mV, at which voltage gated NA+ channels will open, generating an action potential
Threshold
Small localized short-lived change in voltage across the cell membrane following the opening of ligand-gated channels
Local potentials
Change in membrane potential making the inside of the cell more positive, increasing the likelihood that the cel will have an action potential
Depolarization
Change in membrane potential making the inside of a cell more negative relative to the resting potential, reducing the likelihood that the cell will fire an action potential
Hyperpolerization
Small localized membrane depolarizations of a post synaptic neuron that result from neurotransmitters binding to specific receipts that open ion channels. Move the membrane potential closer to the threshold for firing
Excitatory post - synaptic potentials (EPSPs)