Exam 1 Flashcards
ATP is made up of adenosine which is a nucleotide plus a ______ sugar
Ribose
3 steps of translation
initiation, elongation, and termination
Allosteric binding occurs where
Somewhere other than the enzymes binding site
A negative allosteric site changes the shape of the enzyme to have a _______ active site
Less
Important for proper nutrient sensing and stress regulation by maintaining proper cell signaling and transcription rates
O-GlcNAcylation
A protein important for preventing oxidative stress
Glutathione
The modifications to DNA structure that affects transcription
Epigenetics
Protein which binds to dna and initiates the transcriptional process
Transcription factor
Works with transcription factors to increase transcription rates
Co-activator
Which bond in ATP carries the most energy
2nd and 3rd phosphate group (pyrophosphate bond)
Where does substrate level phosphorylation occur
Cytosol
T/F, Ox Phos does not require oxygen
False, it needs o2
T/f, substrate level phosphorylation can proceed under anaerobic conditions
True
What are the four enzymes that participate in substrate phosphorylation
Creatine Kinase, phosphoglycerate kinase, pyruvate kinase, and succinyl coa synthetase
Which enzyme catalyzes the formation of citrate from oxaloacetate & acetyl coa in the TCA cycle
Citrate Synthase
This enzyme isomerizes citrate to isocitrate in the TCA cycle
Aconitase
This enzyme catalyzes dehydrogenation in the TCA cycle
Isocitrate dehydrogenase
This enzyme incorporates H2O across double bond of fumarate to form malate
Fumerase
Which reactions in the TCA cycle are non-equilibrium
Citrate synthase, isocitrate dehydrogenase, and a-ketogluterate dehydrogenase
For the non-equilibrium reactions in the TCA, ______ is a negative allosteric effector
NADH