Exam 1 Flashcards

1
Q

What regulates dna supercooling during replication

A

Topoisomerases

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2
Q

Consequences with deamination

A

Can cause substitution

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3
Q

Consequence with depurination

A

Deletion

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4
Q

Thymine diners

A

Caused by uv light, can form with neighboring ptrimidines, may lead to base pair deletion or substitution

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5
Q

Base Excision Repair

A

You remove the deaminated base and causes a gap DNA polymerase adds new nucleotides

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6
Q

Nucleotide excision repair

A

Removes a sequence of nucleotides

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7
Q

Double strand breaks

A

Homologous end-joining

Non-homologous end-joining

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8
Q

Major two ways that cremation structure can be altered

A

Methylation and actyelation

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