Evolutionary genetics Flashcards

0
Q

the theory of descent with modification through variation and natural selection
-based on observations from travel aboard the HMS Beagle (heavily influenced by pacific island flora and fauna) ADAPTIVE EVOLUTION

A

darwin’s evolution

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1
Q

evolution is the change in allele freq over time

A

dobzhansky’s evolution

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2
Q

-a heritable change in one or more characteristics of a pop or species from one generation to the next

A

brooker’s evolution

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3
Q

the diff btween brooker’s micro and macro evolution is ______ and _________ __ __________ _________
-brooker also hinges evo on _____________

A

time
degree of phenotypic change
speciation

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4
Q

group of individuals that potentially interbreed in nature
-problems (asexual organisms, ring species)
WHO??

A

biological species concept

Ernst Mayr

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5
Q

other problems with biological species definition

A

hybrids & introgression
chronospecies
secondary contract

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6
Q

each species is and independently evolving lineage ( a line of descent )

A

general lineage concept (deQuieroz)

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7
Q
habitat isolation
temporal mating isolation
sexual isolation
mechanical mating isolation
gametic isolation
A

prezygotic isolation mechanisms

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8
Q

hybrid inviability
hybrid sterility
hybrid breakdown

A

postzygotic isolation mech

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9
Q

biogerography + cladogenesis =

A

allopatric speciation
parapatric speciation
sympatric speciation

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10
Q

seq of events in evolutionary development

A

phylogeny

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11
Q

diagram depicting a phylogeny

A

phylogenetic tree

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12
Q

phylogenetic trees are based on _______

-having the same relation, common ancest.

A

homology

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13
Q

study of features that are (or are not) shared

A

cladistics (Willi Henig)

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14
Q

shared with distant ancestor

-arose longer ago

A

ancerstral characteristics

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15
Q
  • not shared with distant ancestors

- arose more recent

A

derived character

16
Q

molecular evolution 2 people?

DNA can be used to infer evolutionary relationships

A

Linus Pauling

Emile Zuckerkandl

17
Q

evolutionary reconstructions

  • typically based upon the analysis of DNA from extant species
  • molecular clock( base upon ________ ____, ________ _____ calculated from fossils, which isn’t necessary)
A

phylogenetic tree

mutation rates

18
Q

shared derived character

A

synapomorphy

19
Q

a distantly related organism

20
Q

the monophyletic group in which we are interested

21
Q

the ________ polarizes the tree

22
Q

overall similarities/dissimilarities

23
Q

phenetic method of constructing phylogenetic tree

A

find most similar pair (humans and chimps 145bp)
calculate the avg number of nucleotide substitutions per species
( 145bp/2 = 72.5bp)
calculate the % nucleotide diffs
(72.5bp * 100)/ 10,000 bp = 0.725%

24
_________ _________ or cladistics, minimize the # of mutations required to make tree
maximum parsimony
25
acted upon by natural selection
non-neutral mutations
26
are free to drift (genetic drift)
neutral mutations
27
who? neutral theory of evolution
Kimura
28
for each protein, the rate of evolution is constant for neutral mutations - less critical proteins and polypeptides evolve faster - amino acid substitutions that do not substantially alter function of protein occur more freq
neutral theory of evolution
29
gene duplicaton often precedes the emergence of gene with new functions
neutral theory
30
elimination of ________ _________ and fixation of neutral mutations occur more freq than selection of __________ __________
deleterious mutations | advantageous mutants
31
is neutral theory is true, then neutral mutations rates are __________ -________ are required to calibrate the clock
clockwise | fossils