1
Q

what is the endosymbiosis theory?

A

β†’endosymbiotic theory deals with the origins of mitochondria and chloroplasts

β†’Mitochondria and chloroplasts are believed to have developed from symbiotic bacteria.

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2
Q

what is some evidence for the endosymbiotic evolution of eukaryotic cells?

A

β†’mitochondria have their own circular genome which replicates independently of nuclear DNA
β†’ new mitochondria are produced by fission of existing mitochondria
β†’ all mitochondrial genomes share similarity with the Typhus bacterium β€œRickettsia prowazekii”

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3
Q

what are plastids and where are they found?

A

β†’the plastid is a major double-membrane organelle found in the cells of plants, algae, and some other eukaryotic organisms.

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4
Q

what are plastid genomes and what do they encode?

A

β†’plastids possess their own genome, the plastome, and a specific machinery to decode its genetic information.

β†’plastid genomes encode proteins necessary for plastid function.

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5
Q

what are the four basic processes of multicellularity?

A

β†’spatial organisation
β†’change in form
β†’growth
β†’differentiation

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6
Q

describe why the evolution of the eye is thought of as being convergent

A

β†’The diversity of eyes suggests that they have evolved several times independently (polyphyletic, convergent evolution).

β†’they also have features in common.

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7
Q

what are the common features in eukaryotic eyes?

A

β†’ALL eukaryotes use a homologous family of proteins, opsins, to detect light.

β†’Opsins are G-protein coupled receptors that convert light to nerve impulses.

β†’Eukaryotic opsins share sequence homology and have diverged to detect different wavelengths of light.

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8
Q

what are homologues, paralogues and orthologues?

A

β†’Homologues are related by descent from a common ancestor.
β†’Paralogues are homologues within the same species.
β†’ Orthologues are homologues between species.

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9
Q

how many Hox genes do vertebrates have and how have they arisen?

A

β†’Vertebrates have four Hox gene clusters

β†’which have arisen from two duplication events of an ancestral chromosome.

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10
Q

what does Pax 6 have to do with the development of the eye?

A

β†’Being eyeless is orthologous to Pax6 in humans and mice.
β†’The ectopic (differently placed) expression of the eyeless gene in drosophilia (fruit flies) leads to ectopic eyes.
β†’Pax6 is involved in eye development throughout the animal kingdom.

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11
Q

how can eye loss occur as a result of evolution? and give an example

A

β†’some animals have evolved from surface-dwelling forms to underground forms

β†’Eye loss is a common feature in such animals because eyes are energetically expensive

β†’ Mexican, blind cavefish

β†’Its surface-dwelling ancestor has eyes, but the derived, cave-dwelling form doesn’t.

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12
Q

why are there differences in morphology between animals which are genetically related?

A

β†’morphological differences are established during development.

β†’even though it’s reproductive, selective pressure acts on the adult form.

β†’animals share the vast majority of their genes, but the regulation of gene expression differs between them.

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13
Q

how do we know where Homo-sapiens come from?

A

β†’We can get evidence from the fossil record and from molecular analyses.

β†’Mitochondria are maternally inherited.

β†’The mitochondrial genome replicates independently of the nuclear genome and does not undergo recombination

β†’the male Y chromosome does not have a homologous female chromosome to recombine with.

β†’Changes in sequence of mtDNA and the Y chromosome are due to random mutations over time.

β†’analysis of mtDNA and Y chromosome sequence shows maternal and paternal origin, respectively.

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14
Q

what is the RNA world hypothesis?

A

β†’ early life is thought to have been based on self-replicating and self catalyzing RNA molecules

β†’ catalytic RNAs are present in organisms from bacteria to humans

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15
Q

why did RNA world evolve into DNA?

A

β†’DNA is more stable than RNA

β†’ there is a greater range of protein enzymes and they are more robust

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