evolution + genetics Flashcards

lecture 1

1
Q

when was pre-Darwinian thought

A

19th century Britain

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2
Q

much of the evidence Darwin used to develop his theory was already known

A

Geologist and palaeontologists had evidence that life had existed on earth for a long time and that it had changed over time
Members of a species look similar to each other when compared to another species
But when compared to each other, there are differences between members of a species

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3
Q

theory of the inheritance of acquired traits example by Lamarck

A

Eat leaves from treetop
Stretched their necks, tongues, and legs
These traits are passed onto their offspring

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4
Q

Lamarck’s theory was one of inheritance of acquired characteristics

A

characteristics developed in life would be passed onto the offspring

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5
Q

when did Darwin return from his world trip on the beagle

A

1937

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6
Q

when did Darwin adapt his theory of evolution by

A

1838

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7
Q

who developed the same theory as Darwin

A

Wallace

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8
Q

define functionalism

A

characteristics of living organisms perform useful functions, therefore the best way to understand a biological phenomenon is to try to understand how it is useful to the organism

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9
Q

what was the 3 characteristics that Darwin was impressed by the functional nature of an organisms characteristics

A

structure, colouration, behaviour

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10
Q

define evolution

A

gradual change in the structure and physiology of an organism over generations

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11
Q

define natural selection

A

traits best suited to survival in a specific the environment will be passed onto the next generation

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12
Q

define theory

A

best current explanation of available evidence

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13
Q

define survival of the fittest

A

The individual best suited to their environment will survive to pass on these genes to the next generation

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14
Q

who coined the term survival of the fittest

A

Spencer

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15
Q

what did Spencer use survival of the fittest to justify

A

social darwinsim

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16
Q

Darwins evidence - fossil record

A

Documented the evolution of fossil records through progressive geological layers

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17
Q

Darwins evidence

A

fossil record, anatomical similarity, artificial selection

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18
Q

Darwins evidence - anatomical similarity

A

Described the striking similarities between living species

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19
Q

Darwin’s evidence - artificial selection

A

Pointed out the major changes that had occurred in domestic plants and animals through programmes of selective breeding

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20
Q

taxonomy of living things

A

Domain (eukarya)
Kingdom (animalia)
Phylum (chordato)
Class (mammaalia)
Order (primates)
Family (hominidae)
Genus (homo)
Species (sapiens)
Human (homo sapien)

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21
Q

key factors that separate humans and other apes

A

Upright posture
Opposable thumb
Speech
Mostly hairless

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22
Q

how much does an adult human brain weigh

A

1200g - 1400g

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23
Q

human brain evolution

A

Increased in size
Much of this increase at the level of the cerebrum
Increase in the number of convolutions means a greater volume of the cerebral cortex

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24
Q

define evolutionary psychology

A

Explains human behaviour in terms of evolution

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25
what are the last surviving species of a family that has existed for a very short time
humans
26
rate of evolution
can be rapid
27
what % of known species are in existence
fewer than 1%
28
gene-centred view of evolution - Darwin
Single unit of evolution isn’t the individual organism, it is the gene itself Gene is the thing that ultimately ‘wants to’ replicate and propagate – individuals die but the gene, if successful, can live indefinitely Organisms are merely the vehicles that genes have built up around themselves in order to achieve replication
29
what are the 3 basic factors that Darwin didn't understand which formed the basis of his theory of evolution
Why conspecifics (individuals of the same species) differ from one another How anatomical, physiological, and behavioural characteristics are passed on from parent to offspring How land animals spread across continents
30
what did Mendel show
Showed that traits can be passed from grandparent to offspring, by-passing the parental generation Showed that traits were carried through something other than blood as had been assumed
31
where are genes located
on chromosomes. which are present in the nucleus of every cell
32
how many pairs of chromosomes do humans have
23
33
what is the exception in humans where they don't have 23 pairs of chromosomes
gametes (egg and sperm cells)
34
diploid cells in humans
46 chromosomes (most cells in the body)
35
haploid cells in humans
23 chromosomes (egg and sperm)
36
how do diploid cells replicate
mitosis
37
mitosis
Mitosis generates a complete copy of the cell’s genetic information All new cells contain copies of all 23 matched pairs of chromosomes
38
how are haploid cells created
meiosis
39
meiosis
Only half the number of chromosomes Chromosomes are randomly assigned to each gamete
40
what happens when the sperm fertilises an egg
chromosomes from the mother pair up with the relevant partner chromosome from the father
41
define alleles
2 corresponding genes in a chromosome pair
42
proportion of genes you share with yourself/identical twin
100%
43
proportion of genes you share with biological parents, siblings, children
50%
44
proportion of genes you share with nieces, nephews, grandchildren
25%
45
proportion of genes you share with great-grandparents, cousins, great grandchildren
12.5%
46
how many genes are in our genome according to the human genome project
19,000 - 24,000
47
who was DNA first described by and when
Watson + Crick, 1953
48
what led to the discovery of DNA
Work of Wilkins and Franklin in obtaining images of DNA using x-ray crystallography led to this discovery
49
what is DNA
Molecule composed of 2 chains (made of nucleotides) that coil around each other to form a double helix Carries the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms
50
what are nucleotide base pairs
adenine - thymine cryosine - guanine
51
what are histones
proteins that provide structure for the very long, coiled strand of DNA
52
what are nucleosomes
sections of DNA that are wrapped around each histone
53
what is the estimate that the human genome contains how many base pairs
3,000 million
54
what are the 2 DNA strands called
polynucleotides
55
what are the 4 nitrogen containing nucleobases
adenine, cytosine, guanine, thymine
56
what are the 3 major steps in DNA replication
Unzip the DNA strands (helicase enzyme) Priming of the template strand (enzyme primase) Assembly of the new DNA segment (enzyme polymerase)
57
what are genes
section of DNA
58
what are genes made up of
A, T, C, G - sequences of bases
59
what do genes do
make proteins
60
why are proteins required in genes
Proteins are required for the structure, function and regulation of the body’s tissues and organs
61
what are proteins made up of
amino acids which are attached to one another in long chains
62
define amino acids
hundreds or thousands of smaller units
63
how many different types of amnio acids are there
20
64
how does protein manufacture take place in the surrounding cytoplasm
Ribonucleic acid (RNA) Similar to DNA, but it exists as a single strand, enabling it to move in and out of the cell’s nucleus RNA has the base URACIL instead of thymine
65
process of DNA and protein
Messenger RNA (mRNA) transports the DNA’s instructions from the nucleus into the cytoplasm Genes are translated into amino acids Each amino acid is added to a lengthening strand When the length of the mRNA is finally translated, the completed protein is released
66
why are proteins important
Small alteration in the building of a protein can seriously affect an organism’s chance or survival
67
define epigenetics
Additional molecules on and around the DNA
68
what is the purpose of epigenetics
Serve to ‘switch’ genes on and off