evidence for evolution Flashcards
comparative genomics
new genes are gained by mutation, others are lost by natural selection, genetic drift or other processes, code in DNA is different for different species, when speciation occurs new species would have very similar DNA however as new species gradually change through mutation, natural selection etc and they accumulate more and more differences in DNA
- species more distantly related have more differences
- species more closely related share greater portion of DNA
genome
complete set of DNA in each cell of an organism
comparative genomics (definition)
field of biological research where genome sequences of different species are compared, used to reveal diversity of gene composition in evolutionary lineages
endogenous retroviruses
viral sequence that has become part of an organism genome, store genetic info as RNA
chromosomes contain non-coding sequences of bases in DNA sequences (junk DNA) they serve no apparent function or purpose
- more closely related species have more common junk sequences
- less closely related species have less common junk sequences
endogenous retrovirus ( process of becoming an erv)
- reverse transcription: upon entering cell retrovirus copies its RNA genome into DNA its then inserted into one of host cells chromosomes
- retrovirus will only become endogenous if it inserts into cell whos chromosomes will be inherited by next generation (sperm or egg cell)
- offspring if individual will have copy of erv at same place in same chromosome in every single one of cells
- all subsequent generations will have copy of erv at same location
bioinformatics
use of computers to describe molecular components of things, use biochemical analysis to gain info on DNA and proteins and computers to store and analyse it
- can assist evolutionary biologists to trace evolution of large number of organisms by measuring changes in DNA rather than through taxonomy or observations
- annotation: identification of genes in DNA sequence, needs to be computerised, made possible because of start and stop codons
mitochondrial DNA
- in form of small circular molecules 5-10 in each mitochondrion, has 37 genes all of which are essential for mitochondrion to function normally
- 24 of these contain code for making transfer rna molecules which are involved in protein synthesis
- other 13 have instructions for making some of enzymes necessary for reaction of cellular respiration
- inherited from mother but also carried in sperm and provide energy for sperm to swim to egg, after sperm has penetrated egg at fertilisation mitochondria in sperm are rapidly destroyed
- has higher mutation rate
how does mitochondrial DNA provide evidence for evolution
scientists are able to use similarity between mtDNA of any two individuals to estimate closeness of relationship through maternal ancestors, if mtDNA their last common maternal ancestor lived long ago, can be used to track evolution through gene flow, founder effect, track migration routes of ancient people
phylogenetic trees
represent evolutionary relationships between number of organisms derived from common ancestor
- ancestral organism forms base of tree
- organisms arisen from it are placed on ends of branches
- closely related groups are positioned on branches close to one another
protein studies
by comparing type and sequence of amino acids in similar proteins from different species degree of similarity can be established, animals of same species have identical amino acid sequence in proteins
- degree of difference between proteins enables estimate to be made of amount of evolution taken place since two species developed from common ancestor
ubiquitous proteins
number of proteins that appear to be in all species from basic essential tasks that all organisms require for life, carry same function everywhere
cytochrome c
type of ubiquitous protein that shows how protein sequences can provide evidence for evolution, performs essential step in production of cellular energy, contains 104 amino acids:
- 37 of these have been found at same position in every sequenced cytochrome c molecule, strongly suggests these proteins descended from ancestral cytochrome c molecule found in primitive microbe (200 million years old)
cytochrome c: evidence for evolution
to compare cytochrome c they need to be aligned so maximum number of proteins containing same amino acids can be determined, the more similarity between two molecules the more recently they’ve evolved from common ancestor
fossil
any preserved trace left left by an organism that lived long ago e.g bones, shells, teeth, footprints, faeces
characteristics of fossilisation
- hard parts (shell, bones, teeth) fossilise better than soft parts (skin, muscle)
- bottom of sea is best place for fossilisation (anoxic, sediments, pressure)
- must be buried, left un disturbed, compressed by sediments (die and get covered quickly
trace fossils
something such as footprint which has been left behind without any hard material