Evidence-based veterinary medicine Flashcards
What is evidence based veterinary medicine?
Using clinical research to help delivery of clinical care to patients
What should be the first, specific factors defined in the approach to EBVM?
Patient - define patient and conditioning
Intervention - define drug and procedure
Comparator - active drug or placebo
Outcome - define clinical response
After defining the PICO, what should happen next?
Search for best information
Critically appraise it
Apply it to a clinical situation
Review and update as required
What is the weakest type of study?
Expert opinion
What is a case-control study? What is a disadvantage to this?
Compares case with a group of controls
Not blinded or randomised
What is a cross sectional study?
Analysing data from a population at a specific point in time
What is a cohort study? What is the disadvantage to them?
Follow cases of a time period
Not randomised or blind
What is a randomised controlled trial? What are the advantages?
Compare a treatment group to a control
Always randomised, often blind
What are systematic reviews?
Summarise result of controlled trials and studies
What are meta-analysis?
Examinating data from independent studies to determine overall trends
What are the types of controlled trial?
Placebo controlled trial Treatment controlled trial Randomisation Blinding Allocation concealment
What does placebo-controlled trial prove? What are the disadvantages to this?
Proves real effect of the treatment
May not be feasible or ethical
What is a treatment controlled trial? What is a disadvantage to this?
Compares differences between treatments
Doesn’t prove either work
What is randomisation?
Allocating cases to different groups by chance
What is allocation concealment?
The investigator does not influence or know what treatment each case will get
