Eukaryotic Flashcards
How many genes do eukaryotic cells have?
6000-30000
How many genes do bacteria have?
500-4000
Why are eukaryotic genomes larger than prokaryotic?
E ha d regulatory genes, non coding DNA, greater complexity of organism, repeat sequences
What is a promoter?
Part of a gene that controls its transcription
What is a exon?
Transcribed sequence that is represented in the final mRNA
What is an intron?
Inverting sequence that is represented and transcribed and transcribed
What types are repetitive sequences are there?
Interspersed and tandemly
What is interspersed repetitive DNA?
Repeated unit scattered in genome
What is tandemly repetitive DNA?
located at telomeres and centromeres
Describe the chromatin structure
Associated with histones
Protein and DNA
What is heterochromatin?
Highly condensed during interphase
What is euchromatin?
Less condensed during interphase and able to be transcribed
How is chromatin packaged?
Nucleosome is the basic unit of chromatin, 200bp are wrapped around it and packaged into 30nm chromatin fibres
How is chomatin modified?
DNA methylation and acetylation
What is the role of a promoter?
Determines where transcription of gene is initiated and the rate of transcription