Eukaryotes ✅ Flashcards
What are the types of eukaryotic organisms?
- Protozoa
- Fungi
- Helminths
Where is the DNA of a eukaryotic organism?
Contained within a nucleus
What are protozoa?
Unicellular organisms
Describe the structure of a protozoa?
The cytoplasm is surrounded by a plasma membrane, which may have external structures
What external structures might the cell membrane of a protozoa have?
- Cell wall
- Flagella
What is the purpose of a cell wall in protozoa?
Enable it to survive outside of the host
Give an example of a protozoa with a cell wall?
Giardia intestinalis
What is the purpose of a flagella in protozoa?
Propel the protozoa
Give an example of a protozoa with a flagella?
Leishmania
What can protozoa be divided into?
- Spore forming (sporozoa)
- Flagellates
- Ameboid
Give 2 examples of spore-forming protozoa
- Plasmodium
- Toxoplasma gondii
Give 2 example of flagellate protozoa
- Giardia intestinalis
- Trichomonas
Give an example of an amoeboid protozoa?
Entamoeba histolytica
What does entamoeba histolytica cause?
Amoebic dysentery or liver abscess
How do protozoa reproduce?
Sexually and/or binary fission
What might the life cycle of protozoa involve?
Vectors
Give an example of a protozoa whose life cycle involves vectors?
Plasmodium
What is the vector for Plasmodium parasites?
Mosquitoes
Give an example of a waterborne protozoa
Entamoeba histolytica
What is meant by fungi being saprophytes?
They live off dead matter in soil and water
Does the cell wall of fungi contain peptidoglycan?
No
What is the implication of the cell wall of fungi not containing peptidoglycan?
Fungi are not sensitive to antibiotics that inhibit peptidoglycan synthesis
What does the cell wall of a fungi contain?
- Chitin polysaccharide
- ß-glucan
- Ergosterol
What is the implication of the ß-glucan and ergosterol in the cell wall of fungi?
They can be targeted by various anti-fungal drugs
What can fungi be classified into?
- Yeasts
- Moulds
- Dimorphic fungi
What are yeasts?
Simple unicellular organisms
How do years reproduce?
Asexual budding
What yeast is responsible for most disease caused by yeasts in human?
Candida albicans
What structure is produced by moulds as they grow?
Branching filamentous hyphae
What is the role of the branching filamentous hyphae of mould?
Assists with reproduction and acquisition of nutrients
What allows moulds to colonise new environments?
They produce germinative spores
How can germinative spores of moulds be pathogenic?
They can be inhaled
Give an example of a mould that can cause disease when inhaled?
Aspergillus fumigatus
Who can the airborne spores of Aspergillus cause disease in when inhaled?
Immunocompromised hosts
What are dimorphic fungi?
Fungi that take the form of moulds at room temperature, but transform into yeasts at body temperature
Give an example of a dimorphic fungi
Histoplasma capsulatum
Who might histoplasmosis capsulatum cause disease in?
Individuals with HIV infection
What are fungal infections known as?
Mycoses
Where do fungi most often cause infection?
Superficial infections localised to epidermis, hair, and nails
What is a fungal infection of the epidermis known as?
- Tinea corporis if affects body
- Tina pedis if affects feet
What is a fungal infection of the hair known as?
Tinea capitis
What is a fungal infection of the nails known as?
Tinea unguium
What may all forms of tines affecting the skin be referred to as?
Ringworm
What is ringworm typically caused by?
Dermatophytes
What fungal groups do dermatophytes belong to?
- Trichophyton
- Microsporum
- Epidermophyton
When can system fungal infection occur?
In immunocompromised hosts
What are helminths?
Complex multicellular parasitic worms
How big are helminths?
Range in size from microscopic filarial parasites to tapeworms several metres in length
How do helminths reproduce?
Sexually
Do helminths cause acute or chronic disease?
Typically cause chronic disease
What can helminths be classified into?
- Nematodes
- Platyhelminths
What are nematodes also known as?
Round worms
What are platyhelminths also known as?
Flatworms
What can platyhelminths be divided into?
- Cestodes
- Trematodes
What are cestodes also known as?
Tapeworms
What are trematodes also known as?
Flukes
What do nematodes look like?
Worms
Where do nematodes cause infection?
- Intestine
- Blood
- Tissues
Give a nematode causing infection in the intestine?
Enterobius vermitcularis
What does enterobius vermicularis cause?
Pruritis ani in children
Give an example of a nematode that causes infection in the blood?
Wuchereria bancrofti
Give an example of a nematode that causes infection in the blood?
Wuchereria bancrofti
What class of nematode is Wuchereria bancrofti?
Filaria
What does Wuchereria bancrofti cause?
Lymphatic filariasis
Give an example of a nematode that infects tissues?
Onchocerca volvulus
What does Onchocerca volvulus cause?
River blindness
Give 2 examples of cestodes
- Taenia solium
- T. saginata
What do cestodes look like?
Ribbon
How long can cestodes grow?
Up to 10m in length
How do humans become infected with cestodes?
The excreted eggs are ingested by an intermediate host, such as a cow or a pig, and humans become infected by eating meat from this animal
What do trematodes look like?
Flat, leaf-like organisms
What is the intermediate host for trematodes?
Freshwater snails
Give a medically important species of trematodes
Schistosoma