essential pharmacology Flashcards
1
Q
describe basic functions of receptors
A
receptor channels - ionotropic receptors
GPCRs - metabotropic receptors
enzymes - intrinsic enzymatic activity or bound to an enzyme ie insulin or cytokine
integrin receptors - interact with cytoskeleton
2
Q
define receptor
A
3
Q
explain agonist and antagonist
A
4
Q
define affinity and efficacy
A
5
Q
describe relationship between agonist concentration and effect
A
6
Q
define affinity of drug for receptor
A
7
Q
explain idea of efficacy of an agonist
A
8
Q
describe processes of transmembrane signalling
A
9
Q
define sources for intracellular calcium
A
10
Q
explain therapeutic potential of selective agonists
A
11
Q
explain therapeutic potential of selective antagonists
A
