ESRD Flashcards

1
Q

What are the two most common causes of ESRD in the US?

A
  1. DM

2. HTN

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2
Q

What age and race has the highest incidence of ESRD

A

Blacks

75+

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3
Q

How many stages of CKD are there? What stage is ESRD? What should you do in Stage IV?

A

ESRD is stage 5 (GFR~15)

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4
Q

What 5 Sx’s worsen with the progression of CKD?

A
  1. Anemia
  2. Malnutrition
  3. Metabolis acidosis
  4. Secondary Hyperparathyroidism
  5. Hyperkalemia
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5
Q

What two forms of dialysis are offered?

A
  1. Hemodialysis

2. Peritoneal Dialysis

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6
Q

What is the gold standard treatment of ESRD?

A

Kidney transplant

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7
Q

What are 4 absolute indictions for dialysis?

A
  1. Hyperkalemia
  2. Metabolic acidosis
  3. Pleuritis/Pericarditis
  4. GI dysfxn (nausea, vomiting, gastroduodenitis)
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8
Q

What are three forms of hemodialysis Access? what is the most desirable? What is the least desirable?

A
  1. Fistula (best)
  2. AV Grafts
  3. Central venous catheter (worst)
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9
Q

When should you use a AV Graft and what are some complications?

A

use when pts dont have good veins
side fx: bacteremia can adhere to surface
–grafts dont have as good blood flow as fistula

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10
Q

What side fx’s are common in dialysis pts? what should you do about it?

A

Anemia (decreased EPO) - give pts iron IV
Hyperparathyroidism - Cinacalcin
Hypotension - Cardiac problems

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11
Q

What is the target Hb level?

A

10 to 11.5

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12
Q

Which treatment has better survival in the first 1-2 years? what about after 1-2 years

A

Peritoneal dialysis - better than HD during first 2 years

HD - better survival after 2 years

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13
Q

What type of treatment can be used it patient has healthy peritoneal and has good transfer?

A

Cycler - pt can sleep while it is being used

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14
Q

What is a Side fx of Peritoneal Dialysis? how do you combat this?

A
Peritonitis - has to be done sterile (PT COMPLIANCE)
outflow failure
pericatheter leak
ab wall herniation
intestinal perforation
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15
Q

What are contraindications of HD?

A

Hemodynamic instability

recurrent access problems (venous stenosis = SVC syndrome)

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16
Q

What are 4 contraindications of PD?

A
  1. Hypoalbuminemia (<25g/L)
  2. Enlarged polycystic kidney
  3. Cirrhosis with ascites
  4. Hx of abdominal surgery
17
Q

What is the most common cause of death in ESRD?

A

cardiovascular disease

18
Q

What should you do about statin therapy in dialysis patients?

A

Do not initiate statin therapy