Esophageal Disorders Flashcards
Hiatal Hernia Dx
endoscopy or barium studies.
Hiatal Hernia Tx best initial therapy
is weight loss and PPIs.
Hiatal Hernia Tx If symptoms persist
Qx: Nissen fundoplication
Alarm symptoms indicating endoscopy include
Weight loss
Blood in stool (heme-positive stool)
Anemia
Achalasia Dx “most accurate test
Manometry: failure of the lower esophageal sphincter to relax
Achalasia Dx best initial tests
Barium esophagram: “bird’s beak”
Achalasia Dx other tests
CXR: abnormal widening of the esophagus. BUT not sens-esp
endoscopy: normal mucosa AND rule out malignancy
Achalasia Tx
no cure
- Pneumatic dilation:
- Surgical sectioning or myotomy (more effective & dangerous)
- Botulinum toxin injection c3-6m
Esophageal Cancer Dx
Endoscopy**
Barium might be the “best initial test,” never deffinitive
Esophageal Cancer Dx of extention
CT and MRI
PET scan utility at EsophCA
1.- to determine the contents of anatomic lesions if you are not
certain whether they contain cancer.
2.- to determine
whether a cancer is resectable (local). or not, wide MT
Esophageal Cancer Tx
Surgical resection*****
+ Chemotherapy and radiation
Esophageal Cancer palliative Tx
Stent placement is used for lesions that cannot be resected. to improve dysphagia.
Esophageal Spasm Dx
most accurate
test: manometry
Barium studies can show a corkscrew appearance
Esophageal Spasm Tx
CCB and Nitrates
CCB sino TCAntd sino Sildenafil.
PPIs can help
Eosinophilic Esophagitis Dx
Endoscopy shows multiple concentric rings
The most accurate diagnostic test is a biopsy finding eosinophils
Eosinophilic Esophagitis 1Ln Tx
best initial therapy is PPIs and eliminating allergenic foods.
Eosinophilic Esophagitis 2Ln Tx
swallowing steroid inhalers to allow the topical use of steroids
Infectious Esophagitis Etiologic agents
- > 90% Candida in AIDS
- CMV
- Herpes
Infectious Esophagitis once suspected, best first step management
Empiric therapy with fluconazole
Infectious Esophagitis what to do if fluconazole didn’t work
Endoscopy
If Candidiasis confirmed-> IV amphotericin
Infectious Esophagitis Dx diff
Endoscopy:
Large ulcerations=CMV
small ulcerations=HSV
Infectious Esophagitis
CMV, HSV tx
CMV= ganciclovir or foscarnet HSV= acyclovir
Schatzki ring Cx Fx. And it is associated with what pathology?
acid reflux and intermittent dysphagia.
Asoc w hiatal hernia
Schatzki ring Tx
pneumatic dilation in an endoscopic procedure
Plummer-Vinson syndrome PAtho
PVSx=Esoph Web Asoc. iron deficiency anemia and can rarely transform into squamous cell cancer. The iron deficiency is not caused by blood loss.
Plummer-Vinson syndrome Dx
barium studies: more proximal rings.
Plummer-Vinson syndrome Tx
iron replacement at first, may solve the lesion. Then endoscopy + biopsy to r/o CA
Zenker Diverticulum Cx Fx
dysphagia, severe halitosis, and regurgitation of food particles**.
Zenker Diverticulum Dx
Barium
Zenker Diverticulum Tx
Only Qx. No medical therapy.
Never NG tube or upper endoscopy. Danger!
Scleroderma Cx Fx
Reflux + scleroderma/sclerosis
Scleroderma Dx
Manometry: decreased
lower esophageal sphincter pressure
Scleroderma Tx
PPIs as it would be for any person with reflux symptoms
Manometry is the answer for
Achalasia
Spasm
Scleroderma
Mallory-Weiss Tear Patho
upper gastrointestinal bleeding after
prolonged or severe vomiting or retching
Mallory-Weiss Tear Cx Fx
Repeated retching is followed by
hematemesis of bright red blood, or by black stool.
No dysphagia.
Mallory-Weiss Tear Tx
no specific therapy,
and it will resolve spontaneously.
Mallory-Weiss Tear Tx Severe cases
injection of epinephrine to stop bleeding or the use of
electrocautery
Boerhaave syndrome ?
full penetration of the esophagus
Cannabinoid Hyperemesis Syndrome Dx. Also called cyclic vomitting Sx
Hx Cannabis + hot shower “better”
OJO this is not intox nor withdraw, just a gen especific reaction
Cannabinoid Hyperemesis Syndrome Tx
antiemetics (such as ondansetron) or benzodiazepines (such as lorazepam).
stop thc
caustic esophagitis, cx fx
Larynx: hoarse. Stridor=urgent, may intubate
Esoph:drooling!
caustic esophagitis dx
endoscopy to asses damage
caustic esophagitis tx
low severity= liquid diet
high severity= NPO 72h, repeat EGD
NEVER neutralize pH
never induce emesis
stricture path
GERD grade IV
1/3 bottom of esoph
esopho CA path
adenoCA caused by GERD, 1/3 bottom of esoph
SCC: caused by smoking and EtOH at upper 1/3
stricture cx fx
Gerd-> dysphagia -> weight loss
ESO CA cx fx
Gerd-> dysphagia -> weight loss
stricture Dx
Barium shows: symmetric circunferencial loss of the lumen.
EGD Dx ro CA
CA Dx
Barium shows: asymmetric loss of the lumen.
EGD
PET scan or PAN CT to stage/ seek for MT
stricture Tx
PPI high dose
Dilation
CA -tx
Chemo Radiation and Qx