Colon Cancer Screening

Question 1

what’s the Frequency of Screening/

Routine testing

Answer 1

should have a colonoscopy every 10 years beginning

at age 50.

Question 2

when to.. do Screening with a Family History of Colon Cancer if
Single family member

Answer 2

Begin 10 years earlier than the age at which the family
member developed their cancer or age 40, whichever is younger. Repeat the
scope every 5 years if the family member is under age 60

Question 3

when to.. do Screening with a Family History of Colon Cancer if
3 members, 2 generations, 1 premature (before 50):

Answer 3

Hereditary
nonpolyposis colon cancer syndrome (HNPCC) comprises these factors. Start
screening at age 25 with colonoscopy every 1 to 2 years.

Question 4

when to.. do Screening with a Family History of Colon Cancer if Familial adenomatous polyposis (FAP):

Answer 4

FAP is defined as the presence of
thousands of polyps with an abnormal genetic test known as the adenomatous
polyposis coli (APC) test. Start screening with sigmoidoscopy at age 12 every
year.

Question 5

when to.. do Screening if Previous adenomatous polyp:

Answer 5

Patient should have a colonoscopy every 3 to 5

years.

Question 6

when to.. do Screening if Previous history of colon cancer

Answer 6

Patient should have colonoscopy at 1 year

after resection, then at 3 years, then every 5 years.

Question 7

Peutz- Jeghers Syndrome path and asoc. w

Answer 7

multiple hamartomatous polyps in
association with:
Melanotic spots on the lips and skin
Increased frequency of breast cancer
Increased gonadal and pancreatic cancer

Question 8

polyposis screening

Answer 8

Age 8: Peutz-Jeghers
Age 12: FAP, juvenile polyposis

Frequency of colonoscopy screening is increased to every 3 years starting at age
8.

Question 9

Gardner Syndrome associated diseases

Answer 9

is colon cancer in association with:
Osteomas
Desmoid tumors
Other soft tissue tumors

also risk ok cancer of the thyroid, pancreas, and small bowel

Question 10

Gardner Syndrome screening

Answer 10

age of 12 with

sigmoidoscopy.

Question 11

Turcot Syndrome ?

Answer 11

colon cancer in association with:
CNS malignancy
TURBAN IN MY HEAD

Question 12

Juvenile Polyposis? patho

Answer 12

colon cancer in association with:

Multiple hamartomatous polyps

Question 13

Juvenile Polyposis screening

Answer 13

Screen both upper and lower GI tracts at same intervals as FAP

Question 14

Anticoagulation in Colonoscopy: NOACs

Answer 14

Stop NOACs one day before colonoscopy, restart them the day after
colonoscopy

Question 15

Anticoagulation in Colonoscopy: warfarin

Answer 15

Stop warfarin 3–5 days before colonoscopy
3 if metal heart
valves.

Question 16

colon cancer patho

Answer 16

premalignant lesion ->inflamation process + genetics ->

Question 17

what makes a good polyp

Answer 17

tubular
peduncular
small

Question 18

what makes a bad polyp

Answer 18

sessile
villous
large

Question 19

iron def anemia on man and postmenopausal woman is indicative of_______

Answer 19

colon cancer

Question 20

how do you stage colon cancer

Answer 20

PAN CT. chet abd pelvis. depending on that you do chemo or not.

Question 21

what you give for chemo and for biologics

Answer 21

FOLFOX / FOLFIRI is chemo

Vegf-inhibitors bevacizumab Bio

Question 22

what to do if after first screeening yo found 1-2 polyps

Answer 22

rescope in 5-10 years. This is just low risk

Question 23

whats high risk?

And when to rescope

Answer 23

any of these
>=3 polyps
>1cm
villous
high grade displasya.

Rescope in 1-3y

Question 24

what’s mega risk?

Amboss: “Very high risk”

Answer 24

> =10 polyps

piecemeal sessile polyp

Question 25

wath’s no risk

Answer 25

ya find nothing at colonoscopy

Question 26

FAP management

Answer 26

as CA can start at 30+death at 40, you can profilactic colectomy

Question 27

Lynch Sx: or hereditary non -polyposis colorectal CA etiology

Answer 27

DNA mismatch repair defect

Question 28

Lynch Sx: or hereditary non -polyposis colorectal CA and other CAs asociate

Answer 28

CEO
colorectal
endometrial
ovarian

Question 29

Lynch Sx: or hereditary non -polyposis colorectal CA . Relation to family Hx

Answer 29

3 member of their family
in two generations w some CEO (colon, endometrium, ovary) Ca’s
and 1 younger/premature

Question 30

peutx jegher sx

Answer 30

dots on the lips, freckles. He does not have colon cancer, but small bowel CA instead. Even with polyps

Question 31

When to screen for Peutz- Jeghers Syndrome ?

Answer 31

at age 8