Erythema Multiforme Flashcards
1
Q
What is erythema multiforme?
A
A type of hypersensitivity reaction
2
Q
What is the most common trigger?
A
Herpes simplex
3
Q
What forms is it divided into?
A
Minor
Major
4
Q
Describe minor form
A
Erythematous well defined round lesions on extensor surface of peripheries, palms and soles
Evolve at different stages into pathognomonic target lesions
5
Q
In the minor form, is there mucosal involvement?
A
Minimal
6
Q
Are upper or lower limbs more commonly affected?
A
Upper
7
Q
Describe the major form
A
Associated systemic upset
Fever
Severe mucosal involvement
8
Q
What causes it?
A
Viruses - herpes simplex Bacteria - mycoplasma, streptococcus Drugs - penicillin, sulphonamides, carbamazepine, NSAIDS, allopurinol CT disease e.g SLE Sarcoidosis Malignancy
9
Q
How is it managed?
A
No treatment in majority of cases needed
Potent topical steroids to relieve rash discomfort
Treat cause e.g aciclovir for HSV, antibiotics for mycoplasma
Oral steroids if severe
