Equations Flashcards
Alveolar gas equation
(Patm - Ph20)x(FiO2) - PaCO2/R
Respiratory Quotient (R)
0.8 - given by CO2 production/O2 consumption
Patm
Denver = 630
Sea level = 760
Ph20
47
Aa gradient
PAO2 - PaO2
normal = 5-15 (but increases to ~100 at 100% O2)
PaO2/FiO2 ratio
normal > 300
ALI 300-200
ARDS < 200
Oxygenation index (OI)
(MAP x FiO2) / PaO2
DO2
CO x CaO2 x 10
CaO2
(Hgb x SaO2 x 1.34) + (PaO2 x 0.003)
CO
HR x SV
CI
CO/BSA
SVR
(MAP-CVP)/CO
PVR
(MPAP - PCWP)/CO
% dead space ventilation (Bohr Equation)
(PaCO2 - ETCO2)/ PaCO2
normal = 30%
Alveolar gas equation: units!
DO2 = mLO2/min CO = L/min CaCO = mLO2/dL Hgb = g/dL 1.34 mLO2/gHgb 0.003 mLO2/dL/mmHg
Fick Equation
Vgas = Area/Thickness x D x (P1 - P2) D = solubility/square root of molecular weight
Diffusing capacity
DL = Vco/PAco
Laplace’s law
P = (4 x surface tension)/radius
Poiseuille’s law
Pressure-flow characteristics for laminar flow
V = (P x 3.14 x r4)/(8 x n x l) R = (8 x n x l)/(3.14 x r4)
P = pressure, r = radius, n = viscosity, l = length
Resistance
change in P / flow
Reynolds number (Re)
Determines if flow is laminar or turbulent - higher = more likely to be turbulent
(2 x r x v x d)/n
r = radius, v = velocity, d = density, n = viscosity