Charts/Graphs

Question 1

Oxygen-hemoglobin dissociation curve: axis

Answer 1

x - PaO2

y - % Hgb saturation

Question 2

Oxygen-hemoglobin dissociation curve: P50

Answer 2

50% saturation - occurs at 26.6 mmHg PaO2

Question 3

Oxygen-hemoglobin dissociation curve: right shift

Answer 3

decreased affinity for O2 (i.e. higher PaO2 needed for P50)

factors:
- increased temperature, CO2, 2-3 DPG
- decreased pH

Question 4

CO poisoning: mechanism

Answer 4

Competitively binds to Hgb with greater affinity that O2

Question 5

MetHgb: mechanism

Answer 5

Oxidizes Fe on Hgb from ferrous (2+) to ferric (3+) state causing a leftward shift of OHDC (i.e. left shift)