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COMLEX 1 > Equation Review > Flashcards

Equation Review Flashcards

1
Q

volume of distribution

A

Vd = amount of drug in body/plasma drug concentration

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2
Q

half-life

A

t1/2 = 0.7*Vd/CL

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3
Q

drug clearance

A

CL = rate of elimination of drug/plasma drug concentration = Vd*Ke(elimination constant)

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4
Q

loading dose

A

LD = Cp*Vd/F

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5
Q

maintenance dose

A

D = CpCLt/F

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6
Q

sensitivity

A

sensitivity = TP/(TP+FN)

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7
Q

specificity

A

specificity = TN/(TN+FP)

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8
Q

positive predictive value

A

PPV = TP/(TP+FP)

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9
Q

negative predictive value

A

NPV = TN/(FN+TN)

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10
Q

odds ratio

A

OR = a/c / b/d = ad/bc

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11
Q

relative risk

A

RR=a/(a+b) / c/(c+d)

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12
Q

attributable risk

A

AR = a/(a+b) - c/(c+d)

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13
Q

relative risk reduction

A

RRR = 1-RR

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14
Q

absolute risk reduction

A

ARR = c/(c+d) - a/(a+b)

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15
Q

number needed to treat

A

NNT = 1/ARR

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16
Q

number needed to harm

A

NNH = 1/AR

17
Q

cardiac output

A

CO = rate of O2 consumption/(arterial O2 - venous O2)

CO = SV * HR

18
Q

mean arterial pressure

A

MAP = CO * TPR

MAP = 2/3 diastolic + 1/3 systolic

19
Q

ejection fraction

A

EF = SV/EDV = (EDV-ESV)/EDV

20
Q

resistance

A

resistance = driving pressure/flow = viscositylength/pir^4

21
Q

stroke volume

A

SV = EDV - ESV

22
Q

capillary fluid exchange

A

Jv = net fluid flow = Kf[(Pc-Pi)-(pic-pii)]

23
Q

renal clearance

A

Cx = Ux*V/Px

24
Q

glomerular filtration rate

A

GFR = Uinulin*V/Pinulin = Cinulin

GFR = Kf[(Pgc-Pbs) - (pigc-pibs)]

25
Q

effective renal plasma flow

A

eRPF = Upah*V/Ppah = Cpah

26
Q

renal blood flow

A

RBF = RPF/(1-Hct)

27
Q

filtration fraction

A

FF = GFR/RPF

28
Q

Henderson-Hesselbach equation (for extracellular pH)

A

pH = 6.1 + log([HCO3-]/0.03*Pco2)

29
Q

Winters formula

A

Pco2 = 1.5[HCO3-] +8 +/- 2

30
Q

physiologic dead space

A

V.D = V.T * (PaCO2 - PeCO2)/PaCO2

31
Q

pulmonary vascular resistance

A

PVR = (Ppulmartery - Platrium)/CO

32
Q

alveolar gas equation

A

PAO2 = PIO2 - PaCO2/R

COMLEX 1 (14 decks)

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