Epithelium Flashcards

1
Q

What type of junction prevents passage of substances between the cells?

A

Occluding (tight) junctions

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2
Q

What is the main function of stratified squamous epithelium?

A

Protection of the skin under mechanical and thermal stress, as well as desiccation.

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3
Q

Where can simple squamous epithelium commonly be found?

A

Alveoli, blood vessels (endothelium), body cavities (mesothelioma), Bowman’s capsule (kidney).

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4
Q

What are two main functions of simple squamous epithelium?

A
  • Easy gas exchange
  • Fluid circulation (i.e. thin layer of cells)
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5
Q

Where is simple cuboidal epithelium commonly found?

A

Glands, small ducts (exocrine glands), surface of ovary.

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6
Q

What are two main functions of simple cuboidal epithelium?

A

Absorption and secretion.

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7
Q

Where can stereo cilia be found?

A

Ear hairs (immotile microvilli).

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8
Q

Where can microvilli be found?

A

Small intestine (increases surface area for absorption).

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9
Q

Where can cilia be found?

A

Respiratory system and GI system (trap bacteria, and move mucus & fluid).

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10
Q

What 3 structures project from the plasma membrane and are 1st to contact harmful substances?

A

Cilia, microvilli, and stereo cilia.

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11
Q

The apical surface always faces the ____.

A

Lumen.

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12
Q

What are the four types of cell morphology?

A

Squamous, cuboidal, columnar, and transitional.

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13
Q

What are the two main classification criteria for epithelium?

A

Cell number & cell morphology.

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14
Q

The epithelium arises from which 3 embryonic layers?

A

Ectoderm, mesoderm, and endoderm.

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15
Q

Where do mucous glands come from?

A

Salivary glands, surface cells of stomach.

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16
Q

Where do serous glands come from?

A

The pancreas.

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17
Q

What are the two materials of secretion we have learned about?

A

Serous and mucous.

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18
Q

Epithelium lies on what membrane?

A

Basal membrane.

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19
Q

The 3 embryonic origins are closely _____ & _____ to one another.

A

Apposed & adherent.

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20
Q

What junction attaches basal surface of epithelial cells to Basal membrane?

A

Hemidesmosomes (anchoring junction).

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21
Q

Where can simple columnar epithelium be found?

A

Small intestines, colon, stomach, gastric glands.

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22
Q

Where can transitional epithelium be found?

A

URINARY TRACT ONLY, bladder, urethra, ureters.

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23
Q

What is the main function of stratified cuboidal epithelium?

A

Barrier (NOT COMMON).

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24
Q

Which epithelium can be between simple and cuboidal stratified epithelium?

A

Transitional epithelium.

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25
What is the main function of pseudostratified columnar?
Secretion and absorption.
26
What is the embryonic origin of mesoderm?
Mesothelium and Endothelium.
27
What kind of epithelia would you find lining body cavities?
Mesothelium (simple squamous).
28
What kind of epithelia would you find in blood vessels?
Endothelium (simple squamous epithelia).
29
What is found in the respiratory system & GI system and can move mucus and fluid?
Cilia.
30
What is found in the small intestine and increases surface area for absorption?
Microvilli.
31
Where do both serous and mucosa secretion get secreted from?
Submandibular glands.
32
Where does serous secretion come from?
The pancreas.
33
What are the two materials of secretion?
Serous (low glycoprotein) and Mucus (glycoprotein, viscous).
34
Where does mucus secrete from?
Salivary glands and surface cells of the stomach.
35
What type of gland is a cluster of glandular cells considered to be?
A multicellular gland.
36
The thymus, thyroid gland, and pancreas are all considered to be what?
Endocrine glands (organs).
37
What type of gland is individual exocrine cells among other nonsecretory cells considered to be?
A unicellular gland.
38
What type of secretion is characterized by product-filled apical areas of cells being extruded?
Apocrine secretion.
39
What type of secretion involves terminally differentiated cells undergoing complete disruption?
Holocrine secretion.
40
What are the three types of exocrine secretion?
Merocrine secretion, Holocrine secretion, and Apocrine secretion.
41
What type of secretion involves exocytosis of membrane-bound vesicles/secretory granules?
Merocrine secretion.
42
How does paracrine secretion release its products?
Individual cells secrete a substance that doesn't reach the bloodstream but affects other cells within the same epithelium.
43
What is the 3rd main type of secretion besides endocrine and exocrine?
Paracrine.
44
Which gland does NOT have direct contact with apical surface, nor a duct system?
Endocrine gland.
45
Which gland has direct contact with apical surface via ducts?
Exocrine gland.
46
Where/how is glandular epithelium formed?
Derives from a covering epithelium and gains glandular function.
47
Epithelium is avascular tissue but needs an underlying or adjacent ______ conjunctive tissue.
Vascularized.
48
Is epithelium capable of self renewal?
Yes.
49
What is glandular epithelium?
Cells arising from epithelium which have secretory function.
50
What type of junction allows passage of small molecules between adjacent cells?
Gap (communicating junctions).
51
What type of junction seals gap between epithelial cells?
Occluding (tight).
52
What type of junction connects cell-cell & cell-ECM?
Zonula Adheren (anchoring junction).
53
What junction connects cytoskeleton to inner cytoplasmic domain?
Desmosomes (adherent anchoring junction).
54
What are epithelial cells?
Cells that are closely apposed and adherent to one another with specialized junctions.
55
What are cell junctions?
A communication between cells, creating mechanical links, receptor-ligand interactions.
56
What is simple epithelium?
Epithelium that is only one cell layer thick.
57
What is epithelium?
An avascular tissue composed of cells covering the surface of the body and organs.
58
Examples of transient cells?
Neutrophils, eosinophils, basophils, lymphocytes, monocytes.
59
Where can you find keratinized and non-keratinized epithelium?
Stratified squamous.
60
Examples of non-keratinized epithelium?
Skin, esophagus.
61
Non-keratinized epithelium has?
A nucleus.
62
Example of keratinized epithelium?
Skin, hair, nails.
63
Keratinized epithelium has?
No nucleus.
64
What cytoskeleton components can produce apical projections such as cilia, microvilli, and stereo cilia?
Microtubules and actin filament.
65
What are the two kinds of proteins microtubules have and what directions do they travel in?
Kinesin - anterograde (- to +) and Dyneins - retrograde (+ to -).
66
Are microtubules polar or non-polar?
Polar.
67
What are microtubules composed of?
Tubulin dimers.