Epithelial Tissues Flashcards

1
Q

Apical Domains

A

These are surfaces that are in contact with a lumen, i.e. kidney tubule cells and glandular duct cells, or external environment.

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2
Q

Basolateral Domains

A

These include the surfaces of cells that are locked together by special junctional complexes with neighboring cells as well as the surface opposite the apical domain that is in contact with the basal lamina.

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3
Q

Three (germ) layers that epithelial tissues can be derived from

A

Ectoderm, Endoderm, Mesoderm

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4
Q

Basements Membranes consists of two components

A

The basal Lamina, The Reticular Lamina

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5
Q

Basal Lamina

A

Next to the epithelial layer and is 50-80 nm this. It is composed of type IV collagen plus glycoproteins and is PAS+. Absent in lymph vessels and hepatic sinusoids.

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6
Q

Reticular Lamina

A

in contact with underlying connective tissue and consists of argyrophilic fibers, reticular fibers and glycoproteins.

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7
Q

Functions of the basement membrane

A

Selective filtration barrier, scaffold for embryogenesis and regeneration, stabilization of tissue shapes.

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8
Q

Type IV collagen

A

does not have fibers, it is found in the basement membranes.

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9
Q

Layers in Simple epithelial

A

One

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10
Q

Layers in Stratified

A

more than one layer

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11
Q

Shape of squamous cells (side View)

A

Flattened

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12
Q

Shape of cuboidal (side view)

A

Height approx equal to width

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13
Q

Shape of Columnar (side View)

A

height greater than width

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14
Q

Pseudostratified

A

Simple epithelium, appears to be stratified but all cells are in contact with the basal lamina. Pseudostratified may reflect stem cells (shorter cells) that are necessary to balance cell turnover by replacing more mature cells when they become aged or damaged.

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15
Q

Transitional epithelium

A

Thought to be a type of simple epithelium but having the appearance of more than one layer b/c of the positions of the nuclei. (associated with urinary track and may be referred to as urothelium)

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16
Q

Urothelium

A

Transitional epithelium

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17
Q

Simple squamous epithelium

A

Lines lumina of ducts, vessels and other tubular structures. Forms walls of alveoli, bowman’s capsules and inner surfaces of membranous labyrinth and tympanic membrane

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18
Q

Simple cuboidal Epithelium

A

In a side view, cells may be low or high. May have a brush border (kidney tubules) on apical surface compsed of microvilli. Found on surface of ovary, pigmented epithelium of retina, kidney tubules, glands and ducts, terminal bronchioles, choroid plexus, and anterior capsule of lens of eye.

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19
Q

Simple Columnar epithelium

A

Intestinal cells may have striated border on apical surface composed of microvilli. * Ciliated columnar epithelium is found in the upper respiratory tract, uterine tubes, uterus, paranasal sinuses, and the central canal of the spinal cord. *non-ciliated columnar epithelium is found in the digestive tract beginning with the cardia of the stomach, the gall bladder, and in parts of the excretory ducts of glands.

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20
Q

Stratified squamous epithelium

A

Heavily keratinized stratified squamous epithelium is found in the epidermis with connective tissue papillae and in the cornea without connective tissue papillae * lightly or non-keratinized stratified squamous epithelium is found in the esophagus, vagina, lining of the mouth, tongue, and part of the epiglottis.

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21
Q

Stratified cuboidal epithelium

A

seldom found, but may occur in small areas of the anal mucosa, large excretory ducts of some glands, and part of the male urethra.

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22
Q

Stratified columnar epithelium

A

seldom found, occurs in the ducts of adult sweat glands, fornix of the conj of the eye, parts of the male reproductive/urinary tract, the pharynx, and epiglottis.

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23
Q

Pseuodstratified epithelium

A

ciliated pseudostratified columnar epithelium is found in the trachea. *pseudostratified epithelium with stereocilia is found in the epididymis

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24
Q

Transitional Epithelium

A

Associated with urinary system *referred to as urothelium

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25
Q

Two Kinds of Epithelium

A
  1. Covering and Lining, 2. Glandular
26
Q

Epithelial tissues function in

A

protection, especially stratified squamous epithelia

27
Q

Epithelial tissues function to maintain concentration differences ( two examples)

A
  1. Tight Barriers 2. Leaky barriers
28
Q

Epithelia involved in secretion or absorption are typically:

A

Simple or pseudostratified. The height of the cell often reflects the level of secretory or absorptive activity (taller=more active)

29
Q

Digestive tract is most likely to be associated with:

A

simple non-ciliated columnar epithelium

30
Q

The Vagina, esophagus, lining of the mouth, tongue and part of the epiglottis have what type of epithelial

A

Lightly or non-keratinized stratified squamous epithelium

31
Q
A

Simple Squamous

32
Q
A

Simple Cuboidal (Kidney)

33
Q
A

Simple Columnar (Ileum)

34
Q
A

Pseudostratified Columnar

35
Q
A

Transitional Epithelium (ureter)

36
Q
A

Stratified Squamous

37
Q
A

Stratified Squamous

38
Q
A

Stratified Squamous

39
Q
A

Simple Cubodial (submandibular Gland)

40
Q
A

Simple Cuboidal (submandibular Gland)

41
Q
A

Simple Columnar (jejunum)

42
Q
A

Simple Columnar (jejunum)

43
Q
A

Simple Columnar (Ileum)

44
Q
A

Simple Cuboidal (Kidney)

45
Q
A

Simpile Cuboidal

46
Q
A

Simple Low Cuboidal (thyroid)

47
Q
A

Transitional Epithelium (Ureter)

48
Q
A

Transitional Epithelium

49
Q

Simple, non‐ciliated columnar epithelium is most like to be found associated with what?

A

digestive tract

50
Q

Junctional complexes are associated with which cellular domains?

A

basolateral

51
Q

Transitional epithelium is associated with which of the following?

A

urinary

52
Q

The extracellular domains of which of the following bind to molecules in the extracellular matrix such as fibronectin and laminin?

A

integrins

53
Q

Stratified cuboidal epithelium may be found where?

A

part of the male urethra

54
Q

Lightly keratinized stratified squamous epithelium is characteristic of which location?

A

vaginal epithelium

55
Q

Which of the following serve as a major interface between the cadherins that hold adjacent cells together and their actin cytoskeletons?

A

catenins

56
Q

Which of the following are molecular complexes that anchor cells together and reinforce the physical integrity of tissues and the cells that make up the tissues?

A

zonula adherens

57
Q

Which of the following are only associated with the basal domains?

A

hemidesmosomes

58
Q

Which of the following types of cell adhesion molecules is associated with zonula occludens and desmosomes?

A

cadherins

59
Q

The basal lamina is associated with which type of collagen?

A

Type IV

60
Q

Desmocollins and desmogleins belong to which of the following groups of CAMs?

A

Cadherins

61
Q

Which of the following are molecular complexes that primarily serve to prevent paracellular transport?

A

Zonula occludens