epilepsy in adults

Question 1

old AEDs effective in partial and clonic seizures(3)?

Answer 1

valproate, pheytoin, carbamazepine

Question 2

2 old AEDs effective for absence seizures?

Answer 2

ethosuximide and valproate

Question 3

new AEDs for partial seizures?(2)

Answer 3

gabapentin and oxcarbazepine

Question 4

4 new AEDs effective for borad spectrum for partial and generalized seizures

Answer 4

lamotrigine, topiramate, levetiracetam, and zonisamide

Question 5

CYP 450 inducers? (3 main ones and 2 minimal)

Answer 5

carbamazepine

phenobarbital

pheytoin

minimal: oxcarbazepine and topiramate

Question 6

t/f. cyp inducers may lead to:

1. failure of oral contraceptives
2. cause osteopenia, osteoporosis, fractures
3. increase metabolism of androgens and estrogens

Answer 6

true

Question 7

enzyme induction is undesirable in whom? (5 groups of ppl)

Answer 7

women on oral contraceptives

patients of on oral coagulation

transplant pts

AIDS pts on protease inhibitors

Pts predisposed to osteoporosis

effect of inducers not significantly reduced until totally discontinued.

Question 8

older AEDs = caterogy _____drugs

Answer 8

D

Question 9

newer AEDs categor _____ drugs/

Answer 9

C