Epilepsy Flashcards
If the patient in the vignette has had two unprovoked (normal EEG and MRI, no history of trauma/infection) generalised tonic-clonic seizures (GTCS). What medications do we give?
Sodium Valproate
Sodium Valproate is widely used as first-line therapy for GTCS
Antiepiletic that may be used to manage focal seizures but is contraindicated for GTCS and other generalised seizures as it may exacerbate seizure activity?
Carbamazepine
Generalised tonic-clonic seizures what do give for males?
sodium valproate
Focal seizures for first line, what do you give?
lamotrigine or levetiracetam
Absence seizures (Petit mal) for first line what do you give?
ethosuximide
Myoclonic seizures for males what do you give?
sodium valproate
Tonic or atonic seizures for
males what do you give?
Sodium Valproate
Tonic or atonic seizures for
females, what do you give?
lamotrigine
Myoclonic seizures for
females what do you give?
levetiracetam
Absence seizures (Petit mal) for second line what do you give for males?
sodium valproate
Absence seizures (Petit mal), for second line what do you give for females?
lamotrigine or levetiracetam
What medication do you need to avoid in Absence Seizures?
AVOID carbamazepine as it may exacerbate absence seizures
Focal seizures, what do you give for second line ?
carbamazepine, oxcarbazepine or zonisamide
Generalised tonic-clonic seizures what do you give for females?
lamotrigine or levetiracetam
Under what conditions would females be offered Sodium Valproate as first line in generalised tonic-clonic seizures?
girls aged under 10 years and who are unlikely to need treatment when they are old enough to have children
women who are unable to have children may be offered sodium valproate first-line
