Epigenetics

Question 1

Epigenetic Trait

Answer 1

An epigenetic trait is a stably heritable phenotype resulting from changes in a chromosome without alterations in the DNA sequence

Question 2

Nucleosome

Answer 2

A unit of DNA - a segemnt of DNA wound around 8 histones

Question 3

A cell’s epigenetic profile

Answer 3

a collection of tags that tell genes whether to be on or off – is the sum of the signals it has received during its lifetime

Question 4

Adding epigenetic tags ?
Removing epigenetic tags
Reading proteins

Answer 4

methlyases, acetlyases, phosphorylases

demethlyases, deacetlyases, phosphatases

bromodomain, chromodomain, PHD finger, WD40 repeat

Question 5

Epigenetic modifications to histones?

Epigenetics modifcations to DNA ?

Answer 5

post-translational, histone variants, nucleosome redmodelling

DNA methylation, RNA interference

Question 6

Methylation of ?

Answer 6

lysines and arginine

Question 7

Acetylation of ?

Answer 7

lysines

Question 8

Phosphorylation of ?

Answer 8

serine, tyrosine and threonine

Question 9

Methylation of which aa in DNA

Answer 9

cytosine

Question 10

IGF2 moms gene

fathers gene

Answer 10

moms - igf receptor ON
igf gene OFF

Fathers - igf receptor OFF
igf gene ON

Question 11

Epigenetics

Answer 11

alters how the genetic code is read, it doesnt change the genetic code.