Epidemiology 8-Ramdomized trials

Question 1

What is internal validity ?

Answer 1

Generalizability of results •Internal validity –If the study is properly done without major methodologic problems and takes into account all the issues discussed thus far the study is said to have internal validity.

Question 2

Internal validity

Answer 2

Question 3

What is external validity ?

Answer 3

External validity

–We carry out a study in one city and find a new therapy to be better than a current therapy we would like to be able to say that the new therapy is better for the disease regardless of where the patients are treated and not just for patients in that city. ‘

that it can be applied in other places, external to that of the experient.

Question 4

What is phase 1 and phase 2 of U.S food and Drug Administration ?

Answer 4

Question 5

What occurs during phase 3 of phase in testing new drug in the USA ?

Answer 5

Question 6

What happens during the phase 4 of the new drug testing ?