epidemiology Flashcards

1
Q

epidemiology

A

1) study of distribution of disease or a physiological condition in human populations
2) factors that influence this distribution
3) also fits it into a consistent philosophy

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2
Q

odds ratio

A

1) greater than one has a positive association

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3
Q

prevalence

A

1) total number of cases in a papulation at a given time

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4
Q

incidence

A

1) a number of new cases that occur in a population over time1

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5
Q

outbreak

A

1) sudden occurrence of a disease in a community which has never experienced before

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6
Q

epidemic

A

1) widespread occurrence in a community at a particular time

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7
Q

pandemic

A

worldwide epidemic

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8
Q

risk factor

A

1) characteristic that places an individual at increased risk of contracting a disease

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9
Q

risk indicator

A

1) probable risk factor identified through cross sectional studies but not confirmed through longitudinal studies

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10
Q

methodological issues

A

1) examination methods - index systems
2) allow you to exam and score periodontal status of an individual
3) inflammation, plaque, probing depth, CAL, radiographs
4) ex. plaque index, perio index, gingiva index,

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11
Q

periodontal index

A

1) applied to each tooth
2) reversible scoring system
3) 0 healthy - 8 advanced destruction

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12
Q

periodontal disease index

A

1) to assess destructive disease
2) irreversible index
3) applied to 6 teeth
4) 0-6
- 4-6 marks attachment loss

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13
Q

big risk factors

A

1) poor oral hygiene
2) tobacco
3) diabetes
4) genetics

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14
Q

poor oral hygiene

A

1) increase plaque mass or reduced host defense may precipitate episodes of perio destruction
2) observational study
- 8% had rapid progression of perio disease
11% had no progression
8% moderate progression

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15
Q

tobacco

A

1) strongest modifiable predictor of disease
2) 2.7 times more likely to have periodontal disease
3) 19 times more pathogens
4) poor response to period treatment 5)

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16
Q

diabetes

A

1) risk factor
2) two way relationship
3) higher prevalence, extent, and severity of perio disease
4) treatment outcome of well controlled is same as non diabetics

17
Q

genetics as a risk factor

A

1) classic twin studies show genetics are modifiers of periodontal disease
= up to 50% accounted for by genetics
2) 96% of severe cases have IL-1 genotype or were smokers

18
Q

risk indicators

A

1) age
- more risk factors over time
2) sex
- men have poorer oral hygiene
3) socioeconomic status
- lower education and lower access to care
4) race
- african american and hispanic
5) obesity
- more cytokine production
6) alcohol
7) stress

19
Q

prevalence of periodontitis

A

1) one of most widespread among adult americans
2) 67 million have some form
3) leading cause of tooth loss in adults over 45
4) 30-35% off all tooth extraction are due to periodontal disease

20
Q

historical theories of periodontal disease

A

1) 1960s universal susceptibility
- everyone was susceptible
2) 1965 non specific plaque theory
- accumulation of plaque causes periodontitis
- prophy 2-3 times per year and flossing
3) 1975 bacterial specificity theroy
- only certain bacteria can cause periodontitis
- treatment was the same
4) 1985-current host-bacterial interaction theory
- must have a susceptible host to have disease
- not everyone is at risk

21
Q

disease progression varies from

A

1) one to another
2) one site to another
3) one type of periodontal disease to another
4) various progression theories

22
Q

continuous progression theroy

A

1) slow and constant rate through life

23
Q

intermittent progression theory

A

1) periods of activity and inactivity

24
Q

random burst theroy

A

1) short periods of destruction of about 4-7 months alternating with short periods of disease inactivity for 4-7 months

25
Q

asynchronous multiple burst theory

A

multiple bursts of diseased activity occur over short periods followed by indefinite period of remission

26
Q

disease criteria

A

1) bacteria must be present in virulent form
2) must be organized into biofilms and in the right combination in sufficient numbers
3) susceptible host

27
Q

what are plaque and calculus

A

1) plaque
- organized mass consisting mainly of microorganisms that adhere to teeth
2) calculus
- hardened plaque with calcium phosphate

28
Q

summary

A

1) periodontitis is a chronic disease resulting from a complex interplay of bacterial infection and host response, modified by behavior