Epi Continued Flashcards
Risk
A Proportion
Probability of OUTCOME in individual group
Exposed or non-exposed
Aka: Incidence Risk
Where are placebos always located?
The Denominator
What must be equal to adequately and appropriately compare freq. b/w groups?
Population size
Time period
Public Health Surveillance Purpose and Examples
Portray ongoing patterns of disease occurrence
Statistical Significance
E.g. Reportable Disease registry
Field Investigation Purpose
Determines source of disease
Learn about history, clinical spectrum, descriptive epi and disease risk factors
Analytic Studies Purpose
Advance the information generated by Descriptive epi Techniques
Use of a comparison group
Assessing situation from data
Evaluation Purpose
Systematically and objectively determine relevance, effectiveness and impact activity
Linkage Purpose
Collab/communicate with (link) to other public health and healthcare professionals
Policy Development
Provides input, testimony, recommendation regarding disease control
Determinants of Disease
Factors of susceptibility
Etiology/Cause of disease
Transmission modes
Elements that determine occurrence
Natural History of Disease Timeline
- Stage of Susceptibility - Exposure
- Stage of subclinical disease - pathological, onset of disease
- Stage of clinical disease - diagnosis
- Stage of recovery or death
Epi compares groups and events by…?
Counting (frequency)
Dividing
Comparing disease over time
3 Aspects of study before declaring true association
- Check for Confounding or Effect Modification
- Check for Bias
- Check for Statistical significance
Compare and Contrast:
- Case-Fatality Rate
- Cause-Specific Mortality Rate
- Proportional Mortality Rate
Can share the same numerator: # of cause specific deaths
Different denominators:
- CFR: # of cases of disease
- CSMR: # in population
- PMR: # of total deaths
Test for Confounding and Effect Modification
- Calculate Crude
- Calculate for all variables or strata
- Compare Crude and Adjusted
If the RELATIVE difference is >15%, confounding or effect modification does occur.