Epi

Question 1

a finite clinical manifestation of abnormal and excessive excitation of a population of cortical neuron

Answer 1

seizure

Question 2

syndrome characterized by chronic, recurrent seizures unproved by systemic or neurologic insults

Answer 2

epilepsy

Question 3

sequence of events that convert a normal neuronal network into a hyperexcitable network

Answer 3

epileptogenesis

Question 4

involvr loss of awereness and lack of responsiveness

Answer 4

generalization

Question 5

initally aware and responsive but then loss of repsonsiveness and memory over time as seizures full generalize

Answer 5

secondarilygeneralized

Question 6

aware and responsive (focal)

Answer 6

simple partial

Question 7

initially aware and responsive but may have some memory impairment (focal with minor spread)

Answer 7

complex partial

Question 8

duration of 60-90 seconds

Answer 8

simple partial

Question 9

duration of 15-120, awareness memeory and/or consciousness may be imparied as seizure progresses

Answer 9

complex partial

Question 10

begin as simpleand/or complex partial then fully generalize, duration of 30-240 sec

Answer 10

secondarily generalized seizures

Question 11

confusion, somnolence, with or without transient focal deficit can last minutes-hours

Answer 11

postictal phase

Question 12

main mechanism for ASD’s

Answer 12

• enhancement of GABA-mediated inhibition
• reduction of excitatory transmision (ie glutamate)
• mod of ionic conductance ( ie na, ca, k)