enzymes + their regulation Flashcards

1
Q

what happens if their is no enzyme for chem. reaction

A

it will happen at a deeply slower rate or it will be impossible for the reaction to happen

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2
Q

what are enzymes

A

catalyst which speed chemical reactions rates

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3
Q

what are majority of enzymes made of

A

proteins

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4
Q

no enzymes is equal to

A

↓ metabolic pathways = difficulty to maintain life

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5
Q

what is key to homoestasis

A

enzymes

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6
Q

how is reactant called when enzyme act on it

A

substrate

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7
Q

area of enzyme subtracts binds to
(groove or pocket on enzyme made of amino acids)

A

active site

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8
Q

all together they form

A

enzyme substrate complex

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9
Q

Induce fit def

A

conformational changes in shape of enzyme due to contact of active site and substrate

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10
Q

transition state

A

substrate reaches an unstable potential energy

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11
Q

activation energy

A

energy needed to convert reactant into transition state

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12
Q

which barrier decides rate of them reactions

A

activation energy

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13
Q

what are cofactors

A

organic or inorganic molecules which binds or stays with enzymes to help in catalyzation

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14
Q

what does heat contribute in reaction rate

A

it speeds ups the move of reactant movements to reach transition state quickly

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15
Q

what happens when thermal energy is higher

A

it is inappropriate for living organisms ad it denatures proteins and result in cell death

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16
Q

how does enzymes affect activation energy ( EA)

A

they decrease it to permit reactants to reach transition state

17
Q

name the 4 ways Enzymes decrease EA

A
  1. be a template for substrate to join
  2. stress substrate bond
  3. provide favourable microorganism for reaction
  4. participate sometimes in chem. reactions
18
Q

give 5 summary steps of how enzymes work

A
  1. substrate binds to active site
  2. enzyme substrate complex
  3. product formation
  4. product leaves
  5. enzyme return to original shape
19
Q

what do enzymes mostly work with

A

cofactors or coenzymes

20
Q

name examples of organic molecules

A

vitamins ( ex vitamin B)

21
Q

name examples of inorganic molecules

A

metal ions ( iron , copper, zinc)

22
Q

what happens if some enzyme require cofactors don’t have them

A

they are dysfunctional = so the active site is not the right shape for the substrate

23
Q

which 2 types of vitamin B are essential for NAD + and FAD production

A

Riboflavin (VB2) and Niacin ( VB3)

24
Q

what is full name of NAD

A

Nicotinamide adenine dinucleotide

25
Q

what is the energized form of NAD ( low energy form )

A

NADH

26
Q

what is the full name of FAD

A

Flavin adenine Dinuclueotide

27
Q

what is the energized form of FAD ( low energy form )

A

FADH2

28
Q

what do NAD nad FAD work with

A

dehydrogenase enzyme

29
Q

what are NAD nad FAD

A

coenzymes

30
Q

where does NAD and FAD energy come from

A

electrons and hydrogen from glucose breakdown

31
Q

dehydrogenase enzymes

A

remove hydrogen from reactant , glucose to give cofactors

32
Q

what do dehydrogenase enzymes

A

give 2 electrons and 1 hydrogen to coenzymes and convert them into NADH and FADH2

33
Q
A