CR in Mitochondria Flashcards
where must pyruvate cross to complete CR
Through outer + inner membrane through facilitated diffusion and secondary active transport
What is the characteristics of outer membrane
smooth
What is the characteristics of the outer membrane?
convoluted
where does the citric acid cycle occur?
inner membrane
what happens in the absence of O2
no H+ gradient = pyruvate doesn’t cross the membrane and stays in the intermembrane or diffuses back in cytosol
what is the first step of pyruvate oxidation?
One carbon group is removed from Pyruvate and released as CO2 through blood to lungs
what is the second step of pyruvate oxidation
remaining portion of pyruvate is oxidize to convert NAD+ into NADH
How many hydrogens are released in matrix
1 H+
where does pyruvate oxidation occur ?
matrix
what is the third step of pyruvate oxidation
CoA binds with an acetyl group to form Acetyl CoA