CR in Mitochondria Flashcards

1
Q

where must pyruvate cross to complete CR

A

Through outer + inner membrane through facilitated diffusion and secondary active transport

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2
Q

What is the characteristics of outer membrane

A

smooth

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3
Q

What is the characteristics of the outer membrane?

A

convoluted

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4
Q

where does the citric acid cycle occur?

A

inner membrane

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5
Q

what happens in the absence of O2

A

no H+ gradient = pyruvate doesn’t cross the membrane and stays in the intermembrane or diffuses back in cytosol

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6
Q

what is the first step of pyruvate oxidation?

A

One carbon group is removed from Pyruvate and released as CO2 through blood to lungs

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7
Q

what is the second step of pyruvate oxidation

A

remaining portion of pyruvate is oxidize to convert NAD+ into NADH

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8
Q

How many hydrogens are released in matrix

A

1 H+

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9
Q

where does pyruvate oxidation occur ?

A

matrix

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10
Q

what is the third step of pyruvate oxidation

A

CoA binds with an acetyl group to form Acetyl CoA

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11
Q
A
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