Enzymes and Gleevec Flashcards
What is one thing all chemical reactions have?
Activation Energy Barrier
What is Activation Energy Ea?
The amount of energy needed to make a molecule unstable enough for a reaction to occur
What are Enzymes?
Biological catalysts that speed up reactions without depleting the enzyme
True or False? Enzymes lower the Ea
True
What is the substrate?
The reactant that the enzyme works off of
What is the reactant that the enzyme works off of?
Substrate
What is the Active Site?
The part of the enzyme where the substrate fits
What is the part of the enzyme where the substrate fits called?
Active Site
True or False? Each enzyme can catalyze thousands of different cellular reaction
False. Each enzyme has one specific reaction
What happens if an enzyme gets too hot?
It denatures
What happens if an enzyme gets too cold?
Chemical reactions will occur too slowly, killing the cells
Enzymes are named by using the suffix _____
-ase
Enzymes are named by adding -ase onto ___________ OR __________.
The substrate they act on OR the type of reaction they catalyze
True or False? An enzyme can hold a substrate in place for something to act on it.
True
True or False? Substrates cannot accommodate an enzyme if they have different shapes.
False. The Enzyme can change shape to fit
What is the Catalytic Cycle?
A process where molecules are broken down with the help of an enzyme.
What is Induced Fit?
The Active Site changes size to hold the substrate more tightly. Also lowers Ea
What are Cofactors?
Non-protein helpers that bind to the active site to help the reaction occur.
What are examples of Cofactors?
Zinc, Iron, Copper, or Inorganic materials
What are Coenzymes?
Organic Helpers that bind to the active site to help the reaction occur
What is an example of a Coenzyme?
Vitamins
True or False? Coenzymes are Non-organic helpers that help reactions start.
False
What do Enzyme Inhibitors do?
Interfere with an enzyme’s effectiveness
What are the 2 kinds of Enzyme Inhibitors?
Competitive and Noncompetitive
