Enzymes and Gleevec

Question 1

What is one thing all chemical reactions have?

Answer 1

Activation Energy Barrier

Question 2

What is Activation Energy Ea?

Answer 2

The amount of energy needed to make a molecule unstable enough for a reaction to occur

Question 3

What are Enzymes?

Answer 3

Biological catalysts that speed up reactions without depleting the enzyme

Question 4

True or False? Enzymes lower the Ea

Answer 4

True

Question 5

What is the substrate?

Answer 5

The reactant that the enzyme works off of

Question 6

What is the reactant that the enzyme works off of?

Answer 6

Substrate

Question 7

What is the Active Site?

Answer 7

The part of the enzyme where the substrate fits

Question 8

What is the part of the enzyme where the substrate fits called?

Answer 8

Active Site

Question 9

True or False? Each enzyme can catalyze thousands of different cellular reaction

Answer 9

False. Each enzyme has one specific reaction

Question 10

What happens if an enzyme gets too hot?

Answer 10

It denatures

Question 11

What happens if an enzyme gets too cold?

Answer 11

Chemical reactions will occur too slowly, killing the cells

Question 12

Enzymes are named by using the suffix _____

Answer 12

-ase

Question 13

Enzymes are named by adding -ase onto ___________ OR __________.

Answer 13

The substrate they act on OR the type of reaction they catalyze

Question 14

True or False? An enzyme can hold a substrate in place for something to act on it.

Answer 14

True

Question 15

True or False? Substrates cannot accommodate an enzyme if they have different shapes.

Answer 15

False. The Enzyme can change shape to fit

Question 16

What is the Catalytic Cycle?

Answer 16

A process where molecules are broken down with the help of an enzyme.

Question 17

What is Induced Fit?

Answer 17

The Active Site changes size to hold the substrate more tightly. Also lowers Ea

Question 18

What are Cofactors?

Answer 18

Non-protein helpers that bind to the active site to help the reaction occur.

Question 19

What are examples of Cofactors?

Answer 19

Zinc, Iron, Copper, or Inorganic materials

Question 20

What are Coenzymes?

Answer 20

Organic Helpers that bind to the active site to help the reaction occur

Question 21

What is an example of a Coenzyme?

Answer 21

Vitamins

Question 22

True or False? Coenzymes are Non-organic helpers that help reactions start.

Answer 22

False

Question 23

What do Enzyme Inhibitors do?

Answer 23

Interfere with an enzyme’s effectiveness

Question 24

What are the 2 kinds of Enzyme Inhibitors?

Answer 24

Competitive and Noncompetitive

Question 25

What is the function of Competitive Enzyme Inhibitors?

Answer 25

Competes with the substrate by filling the active site

Question 26

How are Competitive Enzyme Inhibitors overcome?

Answer 26

By flooding the enzyme with substrate

Question 27

What is the function of Noncompetitive Enzyme Inhibitors?

Answer 27

Binds at the allosteric site, and changes the shape of the enzyme so it no longer fits with the substrate

Question 28

What is the harm of Enzyme Inhibitors?

Answer 28

Can keep vital actions from occurring

Question 29

What are examples of Enzyme Inhibitors?

Answer 29

Drugs, Pesticides, Poisons

Question 30

What is the function of Gleevec?

Answer 30

To block ATP from binding, which decreases white blood cell production