Enzymes 2 Flashcards

1
Q

Naming of Enzymes

A

adding the suffix “-ase” to the:
- name of their substrate
- word/phrase describing activity
(ex. urease - catalyzes hydrolysis of urea)

discoverers for a broad function, before the specific reaction catalyzed was known. (pepsin from greek word pepsis that means digestion)

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2
Q

What are the seven classes for naming and classifying enzymes?

A

Oxidoreductases
Transferases
Hydrolases
Lyases
Isomerases
Ligases
Translocases

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3
Q

which class of enzymes catalyzes transfer of electrons?

A

oxidoreductases

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4
Q

which class of enzymes catalyzes group transfer?

A

Transferases

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5
Q

which class of enzymes catalyzes hydrolysis?

A

Hydrolases

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6
Q

which class of enzymes catalyzes cleavage of C-C, C-O, C-N, or other bonds by elimination, leaving double bond or rings, or addition of groups to double bonds

A

Lyases

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7
Q

which class of enzymes catalyzes transfer of groups within molecules to yield isomeric forms?

A

Isomerases

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8
Q

which class of enzymes catalyzes formation of C-C, C-N, C-O bonds by condensation reactions coupled to cleavage of ATP or similar cofactor?

A

Ligases

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9
Q

which class of enzymes catalyzes movement of molecules or ions across membranes or their separation within membranes?

A

Translocases

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10
Q

transfer of functional groups to water

A

hydrolysis

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11
Q

What is being catalyzed by Oxidoreductase?

A

Transfer of electrons

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12
Q

What is being catalyzed by Transferases?

A

group transfer

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13
Q

What is being catalyzed by Hydrolases

A

hydrolysis

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14
Q

What is being catalyzed by Lyases?

A

cleavage of C-C, C-O, C-N, or other bonds by elimination, leaving double bonds or rings, or addition of groups to double bonds

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15
Q

What is being catalyzed by Isomerases?

A

Transfer of groups within molecules to yield isomeric forms

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16
Q

What is being catalyzed by Ligases?

A

Formation of C-C, C-O, C-N bonds by condensation reactions coupled to cleavage of ATP or similar cofactor

17
Q

What is being catalyzed by Translocases?

A

movement of molecules or ions across membranes or their separation within membranes

18
Q

formal systematic name of the enzyme catalyzing the reaction ATP +D-glucose → ADP +D-glucose 6-phosphate

A

ATP:D-hexose 6-phosphotransferase

19
Q

indicates that it catalyzes the
transfer of a phosphoryl group from ATP to glucose

A

ATP:D-hexose 6-phosphotransferase

20
Q

Enzyme commission number of ATP:D-hexose 6-phosphotransferase

A

2.7.1.1
(2) class name - transferase
(7) subclass - phosphotransferase
(1) phosphotransferase
with a hydroxyl group as acceptor
(1) the phosphoryl group acceptor

21
Q

trivial name for ATP +D-glucose → ADP +D-glucose 6-phosphate

A

hexokinase

22
Q

A complete list and description of the thousands of known
enzymes is maintained by

A

Nomenclature Committee of the International Union of Biochemistry and Molecular Biology