Enzymes Flashcards
CK isoenzyme that migrates fastest in electrophoresis
CK-BB/CK 1
CK enzyme is found in high concentration in
muscle and brain
Most commonly used method in CK Assay
Oliver-Rosalki-Hess (Reverse/Indirect) Method
What is the best sample used in CK Evaluation
Serum
catalyzes interconversion of lactic and pyruvic acid
Lactate dehydrogenase
LD isoenzyme found in lungs, lymphocytes, spleen
LD3 (HHMM)
LD Isoenzyme with the greatest percentage
LD2 (27-37%)
order of LD in hydrocephalus and seizures
LD2 > LD1
conditions where there is flipped pattern of LD isoenzymes
- acute MI and RI, Hemolysis
LD isoenzyme order in Bacterial Meningitis
LD 5 > 4 > 3 > 2 > 1
increase in LD1 and LD2 constitutes what 2 disorders
- Megaloblastic Anemia
- AMI
LD5 is abundant in
skeletal muscles
LD isoenzyme abundant in cardiac muscle
LD1