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Endocrine Pharmacology > Environmental Toxins > Flashcards

Environmental Toxins Flashcards

1
Q

CO poisoning

A

Give oxygen

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2
Q

Cyanide

A

Higher affinity for Fe3+ than for Fe2+ so induce methemoglobinemia to get CN to disassociate with complex 4
Someone who ate a peach
Sodium nitrate causes cyanide to bind more tightly to heme oxygen

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3
Q

Treatments for cyanide poisoning

A

Nitrates induce methemoglobenemia
Sodium thiosulfate
Hydrocobalamin

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4
Q

Deferoxamine

A 
Binds ferric (Fe3+) to form ferroxamine which is renally excreted
Treats iron poisoning
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5
Q

Lead poisoning

A

Increased urinary excretion of Delta-aminolevulinate (ALA) is a leading indicator of occupational heavy medal poisoning

Treat with EDTA

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Endocrine Pharmacology (10 decks)

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