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bms602 > entry and spread > Flashcards

entry and spread Flashcards

1
Q

S. aureus multiplication

A

can grow in almost any tissue site

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2
Q

S. aureus entry

A

entry via skin to skin contact, injury from contaminated object, inhalation, ingestiion

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3
Q

S. pyogenes multiplication

A

extracellular growth on mucous membranes, skin, deep tissue

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4
Q

S.pyogenes entry

A

person to person via respiratory droplets, skin to skin contact, contact w/ fomite

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5
Q

S. pneumoniae multiplication

A

extracellular growth on mucous membranes of respiratory tract or in blood

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6
Q

S. pneumoniae entry

A

person to person through respiratory droplets

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7
Q

B. anthracis entry

A

point source via innoculation of spores into break in skin, inhalation, ingestion (rare)

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8
Q

B. cereus multiplication

A

can grow in almost any tissue site

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9
Q

B. cereus entry

A

ingestion of contaminated food

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10
Q

L. pneumophila multiplication

A

intracellular growth in alveolar macrophages, prevents maturation of phago-lysosome

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11
Q

L. pneumophila entry

A

inhalation of aerosols of contaminated water

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12
Q

L. monocytogenes multiplication

A

intracellular growth in intestinal epithelial cells, M-cells, macrophages, neutrophils, replicates in cytoplasm - escapes the phagosome

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13
Q

L. monocytogenes entry

A

ingestion of contaminated food

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14
Q

M. tuberculosis multiplication

A

intracellularly in colonies of alveolar macrosphaes, replicating in specialized vacuole and/or possibly cytosol - resistance to phagolysosome digestion components, prevent maturation of phagolysosome

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15
Q

M. tuberculosis entry

A

human to human spread via inhalation of contaminated respiratory secretions

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16
Q

C. diphtheriae multiplication

A

extracellular in oropharynx

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17
Q

C. diphtheriae entry

A

inhalation of contaminated respiratory droplets

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18
Q

B. pertussis multiplication

A

extracellular

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19
Q

B. pertussis entry

A

inhalation of contaminated respiratory droplets

20
Q

E. coli multiplication

A

extracellular (ETEC, EPEC, EHEC), intracellular (UPEC)

21
Q

E. coli entry

A

ingestion, wound infections, endogenous (EPEC person to person)

22
Q

S. enterica ssp. enterica multiplication

A

intracellular in intestinal epithelial cell, M-cells, leukocytes

23
Q

S. enterica ssp. enterica entry

A

ingestion of contaminated food or water

24
Q

Y. pestis multiplication

A

extracellular in lymphatic system

25
Q

Y. pestis entry

A

infected flea bite or aerosolized respiratory droplets

26
Q

Shigella spp. multiplication

A

intracellular in intestinal epithelial cells

27
Q

Shigella spp. entry

A

person to person or via ingestion of contaminated food or water

28
Q

C. perfringens multiplication

A

extracellular anaerobic growth in soft tissue or intestinal tract

29
Q

C. perfringens entry

A

wound infection by spores

30
Q

C. tetani multiplication

A

extracelluar anarobic

31
Q

C. tetani entry

A

point object

32
Q

C. difficile multiplication

A

extracellular anaerobic growth in colon (large intestine)

33
Q

C. difficile entry

A

ingestion or normal flora, facilitated by antibiotics

34
Q

C. botulinum multiplication

A

spores germinate IN FOOD SOURCE - exception infant botulism - spores germinae in intestine

35
Q

C. botulinum entry

A

ingestion of toxin contaminated food, ingestion of spores (infant only)

36
Q

N. gonorrheae multiplication

A

extracellularly in mucosal bsolateral surfaces of urogenital tract

37
Q

N. gonorrheae entry

A

sexual contact w/ infected individual

38
Q

N. meningitidis multiplication

A

extracellularly in mucosal bsolateral surfaces of upper respiratory tract

39
Q

N. meningitidis entry

A

inhalation of contaminated respiratory droplets

40
Q

T. pallidum multiplication

A

extracellular and intracellular

41
Q

T. pallidum entry

A

human to human spread via sexual contact or maternal transfer to child

42
Q

Influenza multiplication

A

genome transcribed and replicated in nucleus

43
Q

Influenza entry

A

inhalation of contaminated respiratory droplets (human to human for A, B, C, animal to human is possible for type A only

44
Q

measles multiplication

A

infects macrophages and dendritic cells of respiratory tract, submucosa, then disseminates via lymph and blood - genome uncoats in cytoplasm

45
Q

measles entry

A

inhalation of contaminated respiratory droplets

bms602 (8 decks)

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