Energy production: glycogen and fat

Question 1

A 1 year old boy has Von Gierke’s disease. His abdomen is large and protuberant and he has frequent bouts of sweating, pallor and general weakness, which are relieved by feeding. Which organ is likely to be enlarged, explaining his protuberant abdomen?

Answer 1

Liver due to glycogen accumulation

Von Gierke’s disease is a glycogen storage disease type 1.