Energy Balance and Appetite Flashcards
1 g of CHO is how many kcals?
4 kcals
1 g of Fat is how many kcals?
9 kcals
1g of Protein is how many kcals?
4 kcals
1g of alcohol is how many kcals?
7 kcals, but noting good/it is toxic
Basal Metabolic Rate accounts for what percentage of calories out?
65%
Non-exercise activity thermogenesis accounts for what percentage of calories out?
20%
Exercise activity thermogenic accounts for what percentage of calories out?
10%
Thermic effect of feeding for what percentage of calories out?
5%
What is resting energy expenditure (RER)
Amount of energy required by the body in resting condition
Conditions for measurements for RER
- Fasted 3-4 hours
- Doesn’t need to be measured following sleep
- No Exercise for 12 hours to test
RER is typically what percentage higher or lower compared to BMR
10% higher
RER or BMR more accurate?
BMR but more restrictive conditions
What is Basal Metabolic Rate (BMR)
Amount of energy needed to maintain basic life metabolic processes at rest
What are the conditions for calculating BMR
- Overnight fast (12 hours)
- Measured in the morning following sleep
- No Exercise for 24 hours prior to test
What 5 factors effect BMR?
- Sex
- Free Fatty mass (More Musclez)
- Age
- pregnancy
- NOT Food
What is the thermic effect of food?
Reflects the energy cost (burned) during food digestion, absorption, and storage
What nutrient has the highest therogenic effect?
Protein
Physical Activity for energy includes what 2 things?
All exercises and non-exercising activities associated with daily living
NEAT
Portion of daily energy expenditure resulting from spontaneous physical activity that is not the result of voluntary exercise
EAT
Number of calories burned when engaging in purposeful excerise
1 hour of intense exercise is how many kcal?
800-1000 kcal
What is Metabolic Equivalent of Task (MET)
Ratio of the rate of energy expended during an activity to the rate of energy expended at rest
What is 1 Met
The amount of O2 consumed while sitting at rest
~3.5mL/kg/min
Is the the response of human energy expenditure to increased PA additive or constrained?
It can be both but can be constrained
-Naturally reduced RMR+DIT+Other because tired and sit after a workout = Not getting steps in
Why are people getting fatter x3
1)Energy IN has increased over time
2)Energy OUT has decreased over time (less manual labour)
3)PA is being engineered out of society
There as been a____% increase in calorie intake since 1961
24%
What percentage of the Canadian diet is processed and ready-to-eat foods?
62%
What is obesity?
A progressive chronic disease characterized by abnormal or excessive fat accumulation that impairs health
What is obesity associated with?
T2D
High BP
Heart Disease
Stroke
Arthritis
Cancer
Etc
True or False PA can stop negative effects determined by BMI
True, a BMI may be high but PA can eliminate the effects
What is BMI?
Universal definition of overweight and obesity
Underweight BMI and Risk
Less than 18.5 kg/m2
Increased
Normal Weight BMI and Risk
18.5-24.9 kg/m2
Least
Overweight BMI and Risk
25.9-29.9 kg/m2
Increased
Obese Class 1 and Risk
30-34.9 kg/m2
High
Obese Class II and Risk
35.0 -39.9 kg/m2
Very High
Obese Class III and Risk
Greater or equal to 40 kg/m2
Extremely High
Body Mass Limitations x3
- Body Composition
- Fat Distribution
- Ethnic Groups and Age
Why is BMI used?
Easy to Use and Calculate
Limited time in society
Odds ratio was higher for Low BMI and High PMF or High BMI and low PBF
High BMI and Low PBF
Direct methods (gold standards) for measuring body composition
MRI
CT
DXA
Indirect Methods for Measuring Body composition Lab Based
Hydrostaic Weighting
BodPod
Indirect Methods for measuring body composition Field Based
Skinfolds
BIA
DEXA
Cost
Time
Technician Skill
Subject Comfort
Error
High
~30 Min
High
Mod-High
1.2%
MRI/CT
Cost
Time
Technician Skill
Subject Comfort
Error
High
~10-45min
High
Moderate
~1.2%
Hydrostatic Weighing
Cost
Time
Technician Skill
Subject Comfort
Error
High
30-60 min
High
Low
2.3%-2.8%
BodPod
Cost
Time
Technician Skill
Subject Comfort
Error
High
10 min
Med
Mod
2-3%
SKF
Cost
Time
Technician Skill
Subject Comfort
Error
Low
10-30min
High
Low
3-3.5%
Bioelectrical Impedance Analysis
Cost
Time
Technician Skill
Subject Comfort
Error
Low
5min
Low
High
3-3.5%
Subcutaneous Adipose Tissue is what % of total body fat
Over 80% of total body fat
Subcutaneous Adipose Tissue stores what
Energy
What tissue is responsible for adrenergic stimulation and endocrine regulation (Adrenaline)
Subcutaneous Adipose Tissue
Where is Subcutaneous Adipose Tissue found?
Glutes, Thighs, Stomach
What % of body fat is Visceral Adipose Tissue?
5-20%
What is the role of Visceral Adipose Tissue?
Protects Organs
Why is excess amounts of Visceral Adipose Tissue fat?
Secretes pro-inflammatory Cytokines
Visceral obesity is associated with what
Metabolic Abnormalities
-Increased risk of T2D and Coronary heart disease
What may mediate insulin resistance?
Visceral Adipose Tissue
Whatt issue is most sensitive to exercise and alc?
visceral Adipose Tissue
Men or Women have more obesity
Men
Men or Women have more VAT fat
MEN
Women or Men have more Subcutaneous Fat
Women
Men accumulate Fat where?
Central Adiposity
Android Obesity
Women accumulate fat where?
Lower body fat accumulation
Gynoid Obesity
True or False a diet high in added sugar or other processed carbs should have no special adverse effects of metabolism or body composition after considering total calorie consumption.
True
Calorie is just a calorie
Higher glucose oxidation occurs with a proteins or fat
Protiens
What is the conventional model for weight gain?
Calorie is Just a Calorie
Overeating increases energy intake and accompanied by decreased energy expenditure, increases circulating metabolic fuels (glucose and lipids) and increase fat storage (anabolic adipose)
Explain the CHO-Insulin Model
Calorie is NOT just a calorie
CHO intake increases insulin secretion, which increases fat storage (anabolic adipose), which decreases circulating metabolic fuels (glucose and lipids) and increases hunger
Hunger results in increased energy intake and decreased energy expenditure
-increasing weight so carbs increase weight gain by increasing hunger
Carb and Fat intake has remained the same despite population weight gain?
True
A Reduced Carb diet had what effect on Fat Oxidation
calorie on calorie compared to RF
Increased Fat Oxidation
A reduced fat diet had what effect on oxidation
calorie on calorie compared to RC
No effect on oxidation
For a cumulative effect of body fat loss one should use a RF or RC diet
RF
What diet RF or RC decreases energy expenditure
RC
What are processed foods typically made of?
Hydrogenated Oils
High Fructose Corn Syrup
Flavouring Agents and Emulsifers
NO FIBRE
Why may processed foods increase weight gain compared to unprocessed foods
Fibre = Hunger and there is limited fibre in processed foods.
Ad libtum how many more calories were consumed on a ultra processed diet compared to unprocessed
500kcal
By 2030 what percentage of the US will be obese
50% obese
Greater the 50% obese in 29 states
25% will have severe obesity
greater the 25% in 25 states
What physiological components control energy intake
1)Afferent peripheral hormonal testing (appetite vs anorexigenic)
2)Central Integrationon
3)Efferent Signaling
4)Behaviour Change
Appetite Inhibiting Hormones x5
CKK
PYY (intestine)
GLP-1 (intestine)
PP (pancreas)
Leptin (adipose tissue)
Appetite simulating hormones
Ghrelin (stomach)
Tonic Appetite Signals are based on what
Body Composition
Fat mass and Fat-Free Mass
What is Orexigenic hormone
Appetite
Anorexigenic means
Satiety
Neuropeptides of Orexigenic
NPY
AgRP
Neuropeptides for anorexigenic hormones
POMC- alpha-MSH
CART
Hormones go to what part of the brain
ARC
Articulate Nucleus (produces the neuropeptides)
What is the role of the vagus nerve
1)Important source of indirect neuronal stimulation
2)Composed of efferent/afferent sensory fibres (goes both ways)
3)May be involved directly with the CNS or indirectly with peripheral peptides
Exercise intensity has what relationship with ghrelin post exercise
Higher intensity = decreased grhelin
Exercise intensity has what relationship with appetite post exercise
Appetite decrease with intensity
What is the relationship between lactate and appetite and grhelin
Increase lactate = longer suppression of appetite and ghrelin
What training should you do to reduce appetite
Interval Training
How is exercise different in women for appetite reduction
When in the menstrual phase, extra hormones act a a prohibitor to energy out= weight gain
Grehlin is decreased