energy and cellular metabolism Flashcards

1
Q

phototrophs

A

energy from sunlight

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2
Q

autotrophs

A

energy from own source

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3
Q

chemotrophs

A

energy from chemical reactions

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4
Q

heterotrophs

A

energy from different sources

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5
Q

polysaccharide» oligosaccharide

A

salivary amylase

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6
Q

oligosaccharides» disaccharides

A

pancreatic amylase

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7
Q

disaccharides» monosaccharides

A

intestinal disaccharidases

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8
Q

metabolism

A

biochemical modification of chemical compounds in living cells and organisms

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9
Q

catabolic pathways
types?

A

reactions which break down
degradative
energy producing
oxidative

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10
Q

anabolic pathways
types?

A

reactions which build up
biosynthetic
energy consuming
reductive

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11
Q

change in gibbs free energy

A

change in enthalpy - Temp* change in entropy

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12
Q

+ change in G

A

temp ^
^ [S]

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13
Q

GTP role

A

protein metabolism

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14
Q

CTP role

A

lipid biosynthesis

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15
Q

UTP role

A

carbohydrate metabolism

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16
Q

metabolism stages

A
  1. breakdown of complex molecules into simple units
  2. conversion of simple units into acetyl coA
  3. ATP production from oxidation of acetyl CoA
17
Q

3 major pathways in glucose oxidation

A

glycolysis
citric acid cycle
oxidative phosphorylation

18
Q

glycolysis

A

use of carbs as fuel
glucose> pyruvate
embden-mayerhof-parnas pathway

19
Q

3 stages of glycolysis

A

investment/priming (glucose > F1, 6-GP)
splitting (»G3P)
energy conservation/ yield (G3P> Pyruvate)

20
Q

glucose > glucose6phosphate

A

hexokinase catalysis

21
Q

glucokinase location

22
Q

G6P&raquo_space; F6P

A

conversion of aldopyranose > ketofuranose

23
Q

glycolysis overall energy gain

A

2ATP net gain for every glucose
2 ATP used in investment and 4 generated in yield

24
Q

reasons for tight regulation of metabolic pathways

A

link supply w demand
to allow response to environmental changes
maintain constant internal environment
to enable different tissues to interact

25
glycolysis control
rate-limiting enzymes enzymes at start of pathway enzymes at branch in pathway (amount/activity of enzyme) controlling accessibility of enzyme to substrate
26
how to control activity of enzyme
conformational change covalent modification
27
ways to control accessibility of enzyme to substrate
compartmentalisation of enzymes/ substrate