Endotoxins Flashcards

Endotoxin, especially Lipid A activated macrophages, complement and coagulation. These are some of the specifics in these pathways.

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1
Q

Il-1

A

Fever

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2
Q

TNF

A

fever, tissue necrosis

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3
Q

Nitric oxide

A

hypotension (shock)

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4
Q

Lipid A activated complement components

A

C3a and C5a

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5
Q

C3a

A

hypotension, edema

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6
Q

C5a

A

neutrophil, chemotaxis

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7
Q

Hageman factor

A

coagulation cascade, DIC

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