Cell Biology

Question 1

Gram (+) cocci

Answer 1

Staph and Strep

Question 2

Gram (-) cocci

Answer 2

Neisseria

Question 3

Clostridium
Corynebacterium
Bacillus
Listeria

Answer 3

Gram (+) Rods

Question 4

Treponena, Leptospira, Bordelia

Answer 4

Gram (-) Spirochetes

Question 5

Characterize Mycobacteria

Answer 5

Acid Fast, high lipid content

Question 6

The Bugs that don’t Gram Stain well…

“These Rascals May Microscopically Lack Color”

Answer 6

• Treponema (too thin)
• Rickettsia (intracellular parasite).
• Mycobacteria (requires acid-fast stain)
• Mycoplasma (no cell wall)
• Legionella pneumophila (primarily intracellular)
• Chlamydia (intracellular parasitel)

Question 7

Where is Reactivation of M. tuberculosis most common

Answer 7

apices of the lung, which has the highest P02

eg., after immune compromised or TNF-a inhibitor use

Question 8

People with chronic granulomatous disease (NADPH oxidase deficiency) have recurrent infections with…

Answer 8

Catalase Positive organisms

(it degrades H2O2 before it can be transformed into microcidal products by myeloperoxodase)
e.g., S. aureus, Serratia, Pseudomonas, Actinomyces, Candida, E. coli.

Question 9

Protein A (S. aureus) binds…

Answer 9

Fc receptor of Ig; prevents opsonization and phagocytosis

Question 10

IgA protease cleaves

Answer 10

IgA; secreted by SHiN (S. pneumoniae, H. influenza type B and Neisseria)
helps bacteria colonize the Respiratory mucosa

Question 11

Virulence Factor ‘M protein’ helps

Answer 11

Group A Streptococcus from being phagocytosed