Endometriosis and Dysmenorrhoea Flashcards

1
Q

What is dysmenorrhoea?

A

Pelvic pain during menstruation. Usually cramping, suprapubic pain.

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2
Q

What is dyspareunia?

A

Pain with sexual intercourse (divided into superficial and deep)

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3
Q

What is dyschezia?

A

Pain with defecation

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4
Q

What is mid cycle pain?

A

Pain usually felt in an iliac fossa due to ovulation (Mittelschmerz)

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5
Q

Where is dysmenorrhoea usually felt?

A
  • Suprapubic
  • thighs
  • low back
  • iliac fossae
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6
Q

What proportion of women experience severe (8-10/10) dysmenorrhea?

A

18-21%

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7
Q

What is primary dysmenorrhoea?

A

Cause unknown; thought to be related to prostaglandin release causing uterine contraction and myometrial angina

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8
Q

What is secondary dysmenorrhoea?

A
  • Endometriosis
  • Adenomyosis
  • Intracavity mass (IUD, polyp, fibroid)
  • Cervical stenosis: haematometra
  • Isolated endometrial pocket post endometrial ablation / non communicating uterine horn
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9
Q

What are the superficial causes of dyspareunia?

A
  • Thrush (candidiasis)
  • Skin conditions
  • Vestibulodynia
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10
Q

What are the skin conditions which may cause superficial dyspareunia?

A
  • Atrophic vaginitis
  • Contact dermatitis
  • Lichen planus
  • Lichen sclerosis
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11
Q

What are the causes of mid - deep dyspareunia?

A
  • Endometriosis
  • Adenomyosis
  • Adhesions
  • Ovarian cysts
  • Pelvic floor (spasm, trigger points)
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12
Q

Examination features in dyspareunia work up?

A

Does anything reproduce pain with sex?

  • Cottonbud prodding if localised tenderness at introitus
  • VE:
  • -prominent tender pelvic floor?
  • -palpate outwards 360 degrees
  • -assess uterus for bimanual tenderness
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13
Q

What is endometriosis?

A

Presence of endometrial glands and stoma outside the uterus

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14
Q

What proportion of women have endometriosis?

A

60-70% women with cyclical pelvic pain symptoms; 10-15% women of reproductive age

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15
Q

What are the theories of endometriosis?

A
  • Implantation spread (retrograde menses)
  • Coelomic metaplasia
  • Congenital rest cells
  • Iatrogenic implantation
  • Metastatic spread (lymphatic and haematogenous)
  • Direct spread
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16
Q

How may endometriosis present?

A
  • Cyclical pain
  • Provoked pain
  • Infertility
  • Incidental finding
17
Q

What are the signs of endometriosis?

A
  • Lower abdo tenderness
  • Tenderness on PV esp lateral fornices and POD
  • Palpable adnexal mass (endometrioma)
  • Palpable vaginal nodule or thickening (in POD)
  • Uterus “fixed”
18
Q

How is endometriosis diagnosed?

A
  • Clinical: 60-70% sens
  • US (traditional, detect endometriomas)
  • Lap: gold standard
19
Q

Treatment of endometriosis?

A
  • Nothing
  • Drugs (analgesics)
  • Drugs to suppress hormonal activity (OCP, progestins, GnRH analogues)
  • Surgery: ablate / excise or radical (hysterectomy etc)
20
Q

What is important to tell the patient prior to initiating treatment for endometriosis?

A

May not fix the pain

21
Q

What is important in treating infertility associated with endometriosis?

A
  • Check all other causes
  • Surgery: remove endometriomas + hydrosalpinges; consider removal of all E
  • Early move to IVF
  • Plan pregnancies sooner rather than later
22
Q

What is adenomyosis?

A

Endometrial glands and stroma in myometrial layer of uterus

23
Q

What are the classic symptoms of adenomyosis?

A
  • Menorrhagia

- Dysmenorrhoea

24
Q

What are the classic signs of adenomyosis?

A
  • Bulky uterus

- Uterus tender on bimanual palpation

25
Q

Treatment options for adenomyosis?

A
  • Nothing
  • Drugs: NSAIDS, OCP, progestins, GnRH analogues
  • Mirena IUD
  • Surgery (hysterectomy / myomectomy, endometrial ablation)
26
Q

What is the natural history of primary dysmenorrhoea?

A

Reduces with:

  • age
  • increasing parity
  • OCP use
27
Q

Treatment options for primary dysmenorrhoea?

A
  • Do nothing
  • NSAIDs
  • OCP
  • Progestins
  • GnRH analogues
  • Mirena IUD
  • Hysterectomy
  • Accupuncture
  • Nifedipine / GTN / busocpan