Endomembrane system Flashcards
What is the function of the endomembrane system?
A group of membranous organelles with the task of modifying, packaging and transporting lipids and proteins and cellular digestion
What is the pathway for proteins?
Nucleus -> ER -> Golgi -> Cell membrane
What are the organelles part of the endomembrane system?
ER
Golgi apparatus
vesicles
Lysosomes
Vacuoles
Plasma membrane
What is the function of the RER
Protein synthesis: mRNA attaches to ribosome on RER and is translated in the lumen of ER. Folds and modifies newly built proteins.
What is the function of Lysosomes?
: acidic vesicles of digestive enzymes that breakdown & recycle food,debris, bacteria, etc
What is the Function of SER
Lipid synthesis and detoxifies drugs/posions
What is the function of the
Endomembrane system
A group of membrane-bound organelles inside a eukaryotic cell.
Includes many organelles that are interconnected by vesicles (little
membrane bubbles
Protein secretion
A process by which a substance is released into the environment
Nucleus
a rounded structure that contains & protects most of a eukaryotic cell’s DNA
Nuclear envelope
the double-membrane that surrounds the nucleus & acts as its barrier
Nuclear Pores
tiny “holes” in the nuclear envelope that allow entry/exit into & out of the
nucleus.
Nucleolus
a small dense structure inside the nucleus where ribosomes are assembled
ER
Endoplasmic Reticulum: membranous structures continuous with the nuclear
envelope.
- ER Lumen: the internal space/compartment of the ER.
1) Rough ER: closer to the nucleus with a rough, ribosome-coated surface.
- Newly built proteins fold & are modified in the rER lumen.
2) Smooth ER : further from nucleus with a smooth, ribosome-free surface.
- Synthesizes lipids & detoxifies drugs/poisons
Golgi Apparatus
Molecules synthesized in the ER (e.g. proteins & lipids) are transported by vesicles to the Golgi apparatus