Endocrinology

Question 1

What are the features of primary hyperaldosteronism?

Answer 1

• Hypertension
• hypokalaemia = muscle weakness

Question 2

What are the main causes of primary hyperaldonsteronism

Answer 2

1. Idiopathic adrenal hyperplasia- 60-70%
2. adrenal adenoma
   3.unilateral hyperplasia
3. familial hyperaldosteronism
4. adrenal carcinoma

Question 3

Management of primary hyperaldonsteronism

Answer 3

Depends on cause
adrenal adenoma: surgery (laparoscopic adrenalectomy)
- bilateral adrenocortical hyperplasia: aldosterone antagonist e.g. spironolactone

Question 4

Causes of hypercalcaemia

Answer 4

1. Primary hyperparathyroidism
2. Malignancy - myeloma, bony mets
3. Drugs : thiazides
4. Dehydration