endocrine system Flashcards

1
Q

What is homeostasis?

A

A state of overall internal chemical and physical stability that is required for the survival of cells and the body

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2
Q

What do homeostatic mechanisms do?

A

Maintain a constant internal environment despite a variable external environment

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3
Q

What does deviation from homeostasis indicate?

A

Disease

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4
Q

What is a set point?

A

The physiological value around which the normal range fluctuates

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5
Q

What is a negative feedback loop?

A

A feedback loop where the the effect opposes the original stimulus

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6
Q

What are the elements of a feedback loop

A

Stimulus, receptor, integrator, effector, response

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7
Q

What is positive feedback?

A

Where the response increases the original stimulus

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8
Q

Pathway of steroids hormones

A

lipid soluble - diffuse directly through the cell membrane

enter the cytoplasm

enter the nucleus

form a hormone receptor complex (transcription factor)

binds to promoter regions of genes

stimulates or inhibits the transcription of those genes

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9
Q

What are the two types of hormones?

A

Lipid hormones

Non lipid hormones, peptides

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10
Q

Pathway of peptide hormones

A

binds to a receptor on the cell membrane
- activates a Secondary messenger

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11
Q

Paracrine

A

Hormone stimulates a nearby cell, travels through extra cellular material

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12
Q

Autocrine

A

The hormone secretion acts on the cell itself or cell type

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13
Q

Which hormones does the anterior pituitary secrete?

A

ACTH, TSG, FSH, LH, GH, prolactin

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14
Q

Which hormones does the posterior pituitary produce?

A

ADH, oxytocin

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15
Q

What does the adrenal cortex secrete

A

Cortisol, aldosterone, sex hormones

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16
Q

What does the adrenal medulla secrete?

A

Adrenaline and noradrenaline

17
Q

What do the ovaries and testes secrete?

A

the ovaries secrete estrogens, progesterone, inhibin, and androgens

estes primarily secrete testosterone and inhibin.

18
Q

What does the pineal gland secrete?

A

melatonin,

19
Q

What does the thyroid secrete?

A

thyroxine (T4) and triiodothyronine (T3), which regulate metabolism and energy use, as well as calcitonin

20
Q

What does thyroid hormone do?

A

are vital for regulating metabolism
growth
development
cardiovascular function
temperature regulation,
lipid metabolism
reproductive health.

21
Q

What does calcitonin do?

A

helps lower blood calcium levels by inhibiting osteoclast activity in the bones and promoting the excretion of calcium by the kidneys

22
Q

What do the parathyroid glands secrete?

A

secrete parathyroid hormone (PTH)

23
Q

What does parathyroid hormone do

A

essential for maintaining calcium homeostasis in the body

  • increases blood calcium levels by stimulating bone resorption
  • enhancing renal calcium reabsorption
  • promoting phosphate excretion
  • activating vitamin D
24
Q

What are normal blood glucose levels?

A

between 70 and 99 mg/dL

25
Q

What is the exocrine function of the pancreas?

A

it produces digestive enzymes (amylase, proteases, and lipase)
- bicarbonate secreted into the small intestine
- substances facilitate the breakdown of carbohydrates, proteins, and fats

26
Q

What is hypothyroidism?

A

insufficient production of thyroid hormones

27
Q

What is hyperthyroidism?

A

excessive production of thyroid hormones

28
Q

What are symptoms of hypothyroidism?

A

increased metabolism and a range of symptoms, including weight loss, rapid heart rate, anxiety, and heat intolerance.

29
Q

What are the symptoms of hyperthyroidism?

A

increased heart rate, weight loss, nervousness, tremors, heat intolerance, fatigue, and changes in menstrual patterns

30
Q

What is pituitary dwarfism?

A

condition caused by insufficient growth hormone production from the pituitary gland

31
Q

What happens to effective circulating blood volume and blood pressure when someone is bleeding internally?

A

internal bleeding causes a decrease in effective circulating blood volume due to the loss of blood. Initially, the body compensates for this loss, but if bleeding persists, blood pressure will ultimately decrease

32
Q

Effect of adrenaline on sweat glands and blood vessels of the skin

A

adrenaline increases sweating by stimulating sweat glands, particularly in response to emotional stress, while simultaneously causing vasoconstriction of blood vessels

33
Q

What is hypovolemic shock?

A

hypovolemic shock is a critical condition resulting from a significant decrease in blood volume,

34
Q

What are some symptoms of hypovolemic shock?

A

Nausea or Vomiting
Fatigue or Weakness
Thirst
Rapid Breathing (Tachypnea)
Confusion or Altered Mental Status

35
Q

What happens to cells if there is insufficient insulin in a diabetic?

A

insufficient insulin in a diabetic leads to impaired glucose uptake by cells, resulting in high blood sugar levels and compensatory breakdown of fat and protein for energy.

36
Q

What is a byproduct of the breakdown of fat?

A

the primary byproducts of fat breakdown are free fatty acids and glycerol, while ketone bodies can also be produced under specific metabolic conditions

37
Q

What happens when ketones build up in the blood?

A

ccumulation can lead to ketoacidosis, a serious condition characterized by metabolic acidosis, dehydration, and a range of distressing symptoms