Endocrine System Flashcards
Chemical signals released into the blood and transported throughout the body
Need target cells in order to initiate a physical response
Hormones
2 criteria on how the signals are transmitted between animal cells
Type of secreting cell
Route taken by the signal in reaching the target
Hormones are secreted into the ECF by endocrine cells and reach their targets via the blood stream
Maintains homeostasis, mediates responses to stimuli, regulates growth and development
Endocrine Signaling
Molecule acts over short distances
Reach target cell by diffusion
Local regulator
Target cells lie near the signaling
Paracrine signaling
Target cell itself is the secreting cell
Autocrine signaling
Plays important role in blood pressure regulation, nervous system function, and reproduction
Local regulator
Function in blood clotting, immune system, and reproduction
Prostaglandin
Neurons form specialized junctions with the target cells
Synapses
signaling where Neurons form specialized junctions with the target cells
Synaptic signaling
Secreted by the neurons at the synapses
Diffuse short distances and bind to receptors on target cells
Neurotransmitters
Specialized neurosecretory cells secrete neurohormones that travel to the target cells
via the bloodstream
Neuroendocrine Signaling
signaling with Chemicals released by animals in their environment
Signaling by Pheromones
Chemicals released by animals in their environment
Serve as :
Mark trails leading to food
Defining territories
Warning of predators
Attracting potential mates
Pheromones
Modified fatty acids
Others are polypeptides, some are gases
Local Regulators
Gas that functions as both local regulator and neurotransmitter
Nitric oxide (NO)
Decrease oxygen in blood → ________ activates an enzyme that results in vasodilation → increase blood flow to tissue
Nitric oxide (NO)
3 classes of hormones
polypeptides, amines, steroids
water soluble homrones
olypeptides and amines
fat soluble homrones
steroids
- Secreted by exocytosis
- Travel freely in the bloodstream
- Bind to cell-surface receptors
-Bind to receptors in nucleus or cytoplasm of target cells
Water-soluble hormones
example of water soluble hormones
- Has multiple effects in mediating body’s response to short-term stress
- Binds to receptors on plasma membrane of liver cells
- Triggers the release of messenger molecules that activate enzymes and result in the release of glucose into the bloodstream
Epinephrine
(Water-Soluble hormones Pathway) Binding of hormones to its receptor initiates a ________________ leading to responses in the cytoskeleton, enzyme activation, or a change in gene expression
signal transduction pathway
- Diffuse across cell membranes
- Travel in bloodstream bound to transport proteins
- Diffuse through the membrane of target cells
- Bind to receptors in nucleus or cytoplasm of target cells
Lipid-soluble hormones
Response is usually a change in gene expression
Lipid-Soluble Hormones Pathway
Binds to its cytosolic receptor → hormone-receptor complex is formed and moves into the nucleus → receptor part will act as a transcriptional regulator of specific target genes
Steroid hormone
Same hormone may have different effects on target cells that have
- Different receptor for the hormone
- Different signal transduction pathway
multiple effects of _____
- Can increase blood flow to major skeletal muscles
- Can decrease blood flow to the GI tract
Epinephrine
Endocrine Tissues and Organs
Endocrine glands
Exocrine glands
Endocrine glands
Thyroid
Parathyroid
Testes
Ovaries
Exocrine glands
Salivary gland
Release of acidic contents from the stomach to the
duodenum
Stimulates endocrine cells to secrete secretin
Causes target cells in the pancreas to increase pH level in duodenum
Secretin
Simple Hormone Pathway
Released from an endocrine cell
Travel through the bloodstream
Interact with specific receptors within a target cell to cause a physiological response
Stimulus is received by a sensory neuron, which
stimulates a neurosecretory cell
Simple Neuroendocrine Pathway
secretes neurohormone, which enters the
bloodstream and travels to target cells
Neurosecretory cell