Endocrine system Flashcards
major endocrine glands
hypothalamus
thyroid
parathyroid
pineal
islets of langerhans
adrenals
pituitary
what does t
what does the thyroid gland secrete?
T3, T4, and calcitonin
T3, and T4 increase metabolism and increase growth development
what do the adrenal glands secrete?
epinephrine and norepinephrine
pancreas secretes…
insulin and glucagon
pituitary gland
the master endocrine gland
makes growth hormone
TSH thyroid stimulating hormone
prolactin
5 diff types of cells in anterior pituitary
Somatotropes –> GH
lactotropes or mammotroph?–> PRL
gonadotropes –> FSH and LH
corticotropes –> ACTH
thyrotropes –> TSH
Graves disease
Body creates antibodies to the TSH receptors on follicular cells
parathyroid
secretes parathormone –> secreted in response to low concentrations of calcium, if this doesnt work then the thyroid will secrete calcitonin
adrenal gland
what are the layers to the adrenal gland regions?
Adrenal cortex and
adrenal medulla –> stress hormone
stimulate sympathetic ANS (epinephrine and norepinephrine)
what are the adrenal cortex zones?
Zona reticularis –> stimulat emasculinizationsandrogens
zona fascuculata –> Glucocorticosteroids - Regulate glucose metabolism (Cortisol, corticosterone, cortisone)
zona glomerulosa –> regulate mineral balance (mineralcorticoids) (ALDOSTERONE)
cushing syndrome
elevated circulating corticosteroid, especially cortisol
effects mroe women than men
caused by ACTH-secreting pituitary adenomas, which lead to pituitary and adrenal histopathology
addisons disease
primary adrenocortical insufficeincy
disorder of the adrenal cortex leading to inadequate production of glucocorticoid and mineralocorticoid hormones.
causes:
incomplete development of the cortex or its destruction by autoimmune disease ,
Severe infection such as tuberculosis , or idiopathic atrophy .
Insufficient corticosteroid hormones result in raised pituitary ACTH levels