Endocrine System Flashcards
What is a hormone?
Hormones – chemical messengers secreted by endocrine glands
What are target cells?
Target cells – cells that have receptors for a hormone
What are some organs of the endocrine system?
- Pineal gland
- Hypothalamus
- Pituitary gland
- Thyroid gland
- Parathyroid gland
- Thymus
- Adrenal gland
- Pancreas
- Gonads:
i. Testis
ii. Ovary
What are the 3 classes of hormones?
- Steroid hormones
- Monoamines (made from a specific amino acid)
- Peptide hormones
Name some types of hormone secretion stimuli
Neural stimuli – Nerve fibers elicit release of hormones
Hormonal stimuli – Specific stimulating or inhibiting hormones control hormone release
Humoral stimuli – Response to changing levels of certain ions and molecules in blood
How do peptide hormones effect their target cells?
- Bind to surface receptors
- Intracellular processes argue activated
Name 3 types of hormone interactions
Antagonistic
Synergistic
Permissive
Give 2 examples of steroid hormones.
- Sex steroids
- Corticosteroids
2 examples of Monoamine hormones
- Dopamine
- Epinephrine
2 examples of peptide hormones
- Insulin
- Oxytocin
Describe the pituitary gland
Protrusion off bottom of the hypothalamus at base of brain
Name the divisions of the pituitary gland
Anterior
Posterior
Name some hypothalamic hormones
Thyrotropin –releasing hormone (TRH)
Corticotropin-releasing hormone (CRH)
Gonadotropin-releasing hormone (GnRH)
Growth- hormone releasing hormone (GHRH)
Prolactin-inhibiting hormone (PIH)
Somatostatin- growth hormone inhibiting hormone
NE hormone and it’s source is?
Norepinephrine
Source: Adrenal Medulla
OT hormone and its source is?
Oxytocin
Source: Posterior pituitary
PIH Harmon and it’s source is?
Prolactin inhibiting hormones (dopamine)
Source: hypothalamus
PRL hormone, and its source is?
Prolactin
Source: anterior pituitary
PTH hormone and its source is?
Parathyroid hormone
Source: parathyroids
T3 hormone, and its source is?
Triiodothyronine
Source: thyroid
T4 hormone, and its source is?
Tetraiodothyronine
Source: thyroid
TRH hormone and its source is?
Thyrotropin releasing hormone
Source: hypothalamus
TSH hormone and its source is?
Thyroid stimulating hormone
Source: anterior pituitary
ADH hormone and its source is?
Antidiuretic hormone (arginine vasopressin)
Source: anterior pituitary
ACTH hormone and its source is?
Adrenocorticotropic hormone (corticotropin)
Source: posterior pituitary
CRH hormone and its source is?
Corticotropin releasing hormone
Source: hypothalamus
DHEA hormone and it’s source is?
Dehydroepiandrosterone
Source: adrenal cortex
EPO hormone and its source is?
Erythropoietin
Source: kidneys, liver
FSH hormone and its source is?
Follicle stimulating hormone
Source: anterior pituitary
GH hormone and it’s source is?
Growth hormone (somatotropin)
Source: anterior pituitary
GHRH hormone and its source is?
Growth hormone-releasing hormone
Source: hypothalamus
GnRH hormone and it’s source is?
Gonadotropin releasing hormone
Source: hypothalamus
IGF’s hormones and its source is?
Insulin like growth factors (somatomedins)
Source: liver, other tissues
LH hormone and its source?
Luteinizing hormone
Source: anterior pituitary
How do steroid hormones effect their cells?
- Freely enter target cells
- Bind to receptors in the nucleus
Describe an antagonistic hormonal reaction.
One hormone opposes the other
Describe a synergistic hormonal effect.
Two or more hormones act together to produce a greater effect
Describe a permissive hormonal effect.
One hormone, enhances target organs response to the second hormone.
Name 5 of the major organs of the endocrine system
Hypothalamus
Pituitary gland
Thyroid gland
Parathyroid gland
Pancreas
Gonads (testes,ovary)
Adrenal gland
Pineal gland
Thymus
Name two differences between the nervous system and the endocrine system.
The nervous system communicates by electrical impulses and neurotransmitters, endocrine uses hormones
Nervous system has local specific effects endocrine has general widespread effects
Nervous system releases neurotransmitters at synapses, endocrine releases hormones into the bloodstream
Name the divisions of the pituitary gland
Anterior and posterior
What is another name for the pituitary gland
Hypophysis
where is the pituitary gland located?
Protrusion off the bottom of the hypothalamus at the base of the brain
What is the function of the hypophysial portal system?
It connects to hypothalamus to the anterior pituitary
Describe the network of the hypophysial portal system
Primary capillaries in hypothalamus
Portal venues
Secondary capillaries
Name some hypothalamic hormones
Thyrotropin
Corticotropin
Gonadotropin
Growth hormone releasing hormone (GHRH)
Prolactin inhibiting hormones
Somatostatin (growth hormone inhibiting hormone)
Describe the function of GnRH hormone in the ovary
Gonadotropin releasing hormone
Promotes secretion of follicle, stimulating hormone and luteinizing hormone
Describe the effects of TRH hormone
Promote secretion of thyroid, stimulating hormone (TSH) and prolactin (PRL)