Endocrine System Flashcards
What is the endocrine system?
Groups of specialized glands that affect the growth, development, sexual activities and health of the entire body
The glands produce chemicals called: HORMONES
Hormones:
Are chemical messengers communicating instructions to other cells of the body
hormones enter the bloodstream and are transported to all parts of the body to control body functions and maintain homeostasis
Homeostasis:
The balance or consistency of the internal function of the body
Secretions of hormones is controlled by the..
Hypothalamus
The nervous system
List the organs of the endocrine system (7)
- Pituitary gland
- Thyroid gland
- Parathyroid glands
- Adrenal glands
- Pancreas
- Ovaries
- Testes
Pituitary gland
Located at the base of the brain
referred to as the “master gland”
The pituitary gland secretes hormones that govern hormonal secretion of other endocrine glands
Produces hormones that affect the adrenal gland, gonads, and thyroid gland
Produces growth hormone which stimulates the growth of bones, muscles and organs
Produces prolactin which enhances breast tissue growth and stimulates milk production
Produces oxytocin which triggers contraction of the uterus in labour and childbirth
Produces antidiuretic hormone which regulates water balance in the body
Thyroid gland
Located in the anterior neck in two lobes that lie on either side of the trachea (throat)
Regulates metabolic activity
Produces thyroid hormones which require iodine for their production - these hormones regulate metabolic activity and serve as a general pacemaker for the body
Produce calcitonin which regulates the amount of calcium in the blood and maintains healthy bones
Parathyroid glands
There are 4 parathyroid glands that are attached to the thyroid
They secrete PARATHYROID HORMONE which helps maintain balance of calcium to maintain healthy bones and body tissue
Adrenal glands
Attached to the upper portion of each kidney are two adrenal glands
They secrete 3 types of steroid hormones called: CORTICOSTEROIDS
This includes:
- Sex hormones (estrogen and androgens) - which maintain secondary sex characteristics i.e breast development, facial hair in men
- Mineralocorticoids - which regulate electrolyte balance
- Glucocorticoids (mainly cortisol) - which help promote normal metabolism, resistance to stress and counter inflammatory response
Another part of the adrenal gland produces epinephrine (adrenaline) and nor-epinephrine which are the “flight or fight” response to stress
Most important function of nor-epinephrine: elevate blood pressure
Pancreas
Located posterior to the stomach and beneath the liver
It functions as both an exocrine and endocrine gland
Has important roles in digestion and regulations of blood sugar levels
The exocrine function is to produce digestive secretions which flow into the small intestine to help digest food
The endocrine function is to produce glucagon and insulin which regulate blood sugar levels in the body
Ovaries
The ovaries are two oval glands located in the pelvic cavity, one on each side of the uterus
They produce the female sex cell, the ovum (egg) as well as the hormones estrogen and progesterone which are responsible for: the development of female sex characteristics and menstrual cycle regulation
Both hormones play an important role in preparing the uterus for implantation of the fertilized egg, in maintaining pregnancy and promoting growth of the placenta
Testes
The testes are two oval glands that lie in the scrotum
They produce:
spermatozoa - which are the male sex cells
testosterone - which controls sexual development and reproductive function
Pathologies of the pituitary gland
These malfunctions may be congenital or may result from a tumour
Congenital: means present from birth
Growth hormone
Malfunction of the pituitary gland in producing growth hormone may result in too little or too much growth
GROWTH HORMONE DEFICIENCY:
Will cause a person to be shorter than average (dwarfism)
GIGANTISM:
Results from excess of growth hormone before puberty and causes excessive skeletal growth
ACROMEGALY:
Occurs when there is an excess of growth hormone in adulthood. It is characterized by enlarged features, particularly of the face, hands and extremities. Has negative effects on the heart
Pathologies of the thyroid gland
- GOITER - enlargement of the thyroid gland due to a lack of iodine in the diet (salt). May also result from inflammation, infection, tumor, or malfunction of the thyroid gland
- HYPOTHYROIDISM- decreased function of the thyroid gland produces a decrease in metabolic rate, fluid retention, obesity and fatigue
- HYPERTHYROIDISM- increase function of the thyroid gland results in increased metabolic rate, nervousness, constant hunger, palpitations, weight loss and fatigue
“Graves’ disease” which may cause hyperthyroidism, causes protrusion of the eyeballs